A0A2C9C376 · A0A2C9C376_CAEEL
- Proteinnon-specific serine/threonine protein kinase
- Genepar-1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids1129 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Publications for A0A2C9C376
A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans.
- SourceWormBase: WBGene00003916, WormBase: WBGene00003916
Cited inMapped topar-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed.
- CategoryExpression, Phenotypes & Variants, Sequences
- SourceWormBase: WBGene00003916, WormBase: WBGene00003916, WormBase: WBGene00003916, WormBase: WBGene00003916
Identification of genes required for cytoplasmic localization in early C. elegans embryos.
- CategoryPhenotypes & Variants
- SourceWormBase: WBGene00003916
Inhibition of PAR-1 delays aging via activating AMPK in <i>C. elegans</i>.
- AnnotationInhibition of PAR-1 delays aging via activating AMPK in C. elegans.
- CategoriesFunction, Phenotypes & Variants
- SourceGeneRif: 179912
Spatial regulation of the polarity kinase PAR-1 by parallel inhibitory mechanisms.
- Annotationasymmetric localization of PAR-1 protein is not essential and that PAR-1 kinase activity is regulated spatially in Caenorhabditis elegans zygotes
- CategoriesFunction, Subcellular Location
- Source
Establishment of the PAR-1 cortical gradient by the aPKC-PRBH circuit.
- Annotationa circuit consisting of aPKC and the PRBH-domain protein ensures the local recruitment of PAR-1 to a well-defined cortical compartment
- CategoriesFunction, Interaction, Subcellular Location
- SourceGeneRif: 179912, WormBase: WBGene00003916
A continuum of mRNP complexes in embryonic microRNA-mediated silencing.
- CategoryInteraction
- SourceWormBase: WBGene00003916
Multisite Phosphorylation of NuMA-Related LIN-5 Controls Mitotic Spindle Positioning in C. elegans.
- CategoryInteraction
- SourceWormBase: WBGene00003916
Phosphorylation of FEZ1 by Microtubule Affinity Regulating Kinases regulates its function in presynaptic protein trafficking.
- AnnotationPhosphorylation of FEZ1 by par-1 regulates its function in presynaptic protein trafficking.
- CategoriesFunction, Interaction
- SourceGeneRif: 179912, WormBase: WBGene00003916
The 14-3-3 protein PAR-5 regulates the asymmetric localization of the LET- 99 spindle positioning protein.
- AnnotationResults indicate that PAR-5 protein acts in a mechanism with PAR-1 protein to regulate LET-99 protein cortical localization.
- CategoryFunction, Interaction
- SourceGeneRif: 179912, WormBase: WBGene00003916
A combined binary interaction and phenotypic map of C. elegans cell polarity proteins.
- CategoryInteraction
- SourceWormBase: WBGene00003916
A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi.
- CategoryInteraction
- SourceWormBase: WBGene00003916
Spatiotemporal transcriptomics reveals the evolutionary history of the endoderm germ layer.
- CategoryExpression
- SourceWormBase: WBGene00003916
PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo.
- AnnotationDNA replication is asymmetrically regulated in the two-cell stage embryo and the PAR-4 and PAR-1 polarity proteins dampen DNA replication dynamics specifically in the posterior blastomere.
- CategoryFunction
- SourceGeneRif: 179912
par-1, atypical pkc, and PP2A/B55 sur-6 are implicated in the regulation of exocyst-mediated membrane trafficking in Caenorhabditis elegans.
- AnnotationThe par-1 protein is a possible cooperation and involvement in postembryo lethality developmental timing as well as SNARE protein trafficking.
- CategoryFunction
- SourceGeneRif: 179912
The million mutation project: a new approach to genetics in Caenorhabditis elegans.
- CategoryPhenotypes & Variants
- SourceWormBase: WBGene00003916
Prediction of C. elegans longevity genes by human and worm longevity networks.
- CategoryPhenotypes & Variants
- SourceWormBase: WBGene00003916
Caenorhabditis elegans screen reveals role of PAR-5 in RAB-11-recycling endosome positioning and apicobasal cell polarity.
- CategoryPhenotypes & Variants
- SourceWormBase: WBGene00003916
RNA surveillance is required for endoplasmic reticulum homeostasis.
- CategoryPhenotypes & Variants
- SourceWormBase: WBGene00003916