A0A2C8F3H8 · A0A2C8F3H8_9BACT

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site23Important for substrate specificity
Active site81Proton acceptor
Site82Important for substrate specificity
Site165Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      DPRO_0264

Organism names

  • Taxonomic identifier
  • Strain
    • 500-1
  • Taxonomic lineage
    Bacteria > Thermodesulfobacteriota > Desulfovibrionia > Desulfovibrionales > Desulfovibrionaceae

Accessions

  • Primary accession
    A0A2C8F3H8

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    203
  • Mass (Da)
    22,119
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    0D18AE1D9B2E1419BA6D347EE669DBD6
MNNTATGPFQSEKEIVLASGSPRRKELLQGLGLDLTIQPSTLDEPLPEDDESPQEYALRMAEMKTRDVANQHPDATVIGADTIVVLNDRIMGKPHNEEDALNMLKALAGEKHQVITAFCIILDNSKAVTQAVVTDVYMRESSDKELLGYIATGEPVDKAGAYAIQGIGTFLVKDIKGSYTNVVGLPLTEVIETLVQWRVIAAR

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LT907975
EMBL· GenBank· DDBJ
SOB57143.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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