A0A2B4ECZ9 · A0A2B4ECZ9_9BACI

  • Protein
    Undecaprenyl-diphosphatase
  • Gene
    uppP
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionundecaprenyl-diphosphatase activity
Biological Processcell wall organization
Biological Processdephosphorylation
Biological Processpeptidoglycan biosynthetic process
Biological Processregulation of cell shape
Biological Processresponse to antibiotic

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-diphosphatase
  • EC number
  • Alternative names
    • Bacitracin resistance protein
    • Undecaprenyl pyrophosphate phosphatase

Gene names

    • Name
      uppP
    • ORF names
      COL05_30320

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • AFS059628
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus

Accessions

  • Primary accession
    A0A2B4ECZ9

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane41-61Helical
Transmembrane81-101Helical
Transmembrane107-127Helical
Transmembrane186-204Helical
Transmembrane216-236Helical
Transmembrane248-264Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the UppP family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    265
  • Mass (Da)
    29,138
  • Last updated
    2017-12-20 v1
  • Checksum
    DD9CF4E6B1CC1DF7
MSDIIIAFILGIIEGLAEFLPISSTGHLILVGHLLGFEGERAKTFEIVIQLGAILAIAILYHKRLVSLCNIKPLLRKEKKFNVFHVFLGVFPAVVAGLLLHDVIKTYLFQPYTVVIGLVAGAILMIFAEVKKKEATAYSLDDLTYRQALTIGLFQCLAVYPGFSRAGSTISGGLLAKVNYKTASEFSFLIALPVMVGATGLDLLKSWKYLSVNDIPMFVVGFITSFIVAMLAVVTFLKLLEKIGLKPFAYYRILLAILFTLFVLL

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NVEC01000136
EMBL· GenBank· DDBJ
PFV68394.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp