A0A2A8YLN2 · A0A2A8YLN2_BACAN

  • Protein
    Cyclic-di-AMP phosphodiesterase
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    2/5

Function

function

Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP).

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Note: For phosphodiesterase activity, probably binds 2 Mn2+ per subunit.

Features

Showing features for binding site.

165750100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site345Mn2+ 1 (UniProtKB | ChEBI)
Binding site349Mn2+ 1 (UniProtKB | ChEBI)
Binding site351Mn2+ 2 (UniProtKB | ChEBI)
Binding site420Mn2+ 2 (UniProtKB | ChEBI)
Binding site420Mn2+ 1 (UniProtKB | ChEBI)
Binding site444Mn2+ 2 (UniProtKB | ChEBI)
Binding site499Mn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionhydrolase activity
Molecular Functionmetal ion binding
Molecular Functionnucleic acid binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Cyclic-di-AMP phosphodiesterase
  • EC number

Gene names

    • Ordered locus names
      GBAA_5719

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Ames ancestor
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus > Bacillus cereus group

Accessions

  • Primary accession
    A0A2A8YLN2
  • Secondary accessions
    • A0A1J9VMZ0
    • A0A2B6C5E0
    • E9QWM5
    • E9QWM6
    • Q6HQ28

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane9-27Helical
Transmembrane33-53Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain173-301GGDEF

Sequence similarities

Belongs to the GdpP/PdeA phosphodiesterase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    657
  • Mass (Da)
    74,292
  • Last updated
    2020-10-07 v1
  • Checksum
    C8E7D7D77DBB61A8
MPEFYKKQWFLYPVYVLAFFVFVLISILCYFHLMMGIISFFIFCIVLFVVVRFELTFQKNFEKHTTDMITRVKKVSNEAFNQMPIGILLYNKDYGIDWANPYLSSCLGQHALAGWHLYDVSETLLLFIKGETSDDIVSLNNRKFRVFVRKEEKLIYFFDVTEQTEIEKMYEDQRTVLAVIYLDNYDEVTQGLDDQLRTNITSLVTSRLNEWAVKYGAYLKRASSERFFVVLNESILAQMEKGKFSILDQVREETSKRNIPLTLSVGVGSGDLPLSELGAMAQSGLDLALGRGGDQVAIKQATGKVKFYGGKTNPVEKRTRVRARVISHALKDLVLESSNVIIMGHRAPDMDAIGAAIGILKVAQLNERKGYIVLDENDSDKGIKRLMDKVKQNEELWSHFITPEQAMEFANDDSLLVVVDTHKPSMVMEEKLLRKIENVVVIDHHRRGEDFIEDPLLVYMEPYASSTAELVTELLEYQPKNLKMTMLEATALLAGIIVDTKSFTFRTGARTFDAASYLRSHGADTVLVQELLKEDMDQYLRVAKAIKNAYIYTNGIAIAKVDSDDYYDQVLIAQSADTLLTMTGIIASFVIAKRGENFIGISGRSLGEVNVQLIMENLGGGGHLTNAATQMKNVTVDEAEEKLRFVIDDYLQGGTQS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE017334
EMBL· GenBank· DDBJ
AAT34880.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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