A0A2A7GVI7 · A0A2A7GVI7_9BACI
- ProteinPhosphoenolpyruvate carboxykinase (ATP)
- GenepckA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids528 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
Catalytic activity
- oxaloacetate + ATP = phosphoenolpyruvate + ADP + CO2
Cofactor
Note: Binds 1 Mn2+ ion per subunit.
Pathway
Carbohydrate biosynthesis; gluconeogenesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 56 | substrate | ||||
Sequence: R | ||||||
Binding site | 192 | substrate | ||||
Sequence: Y | ||||||
Binding site | 198 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 198 | Mn2+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 198 | substrate | ||||
Sequence: K | ||||||
Binding site | 217 | ATP (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 217 | Mn2+ (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 233-241 | ATP (UniProtKB | ChEBI) | ||||
Sequence: GLSGTGKTT | ||||||
Binding site | 254 | Mn2+ (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 282 | ATP (UniProtKB | ChEBI) | ||||
Sequence: E | ||||||
Binding site | 319 | ATP (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 319 | substrate | ||||
Sequence: R | ||||||
Binding site | 444 | ATP (UniProtKB | ChEBI) | ||||
Sequence: T |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | kinase activity | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoenolpyruvate carboxykinase (ATP) activity | |
Biological Process | gluconeogenesis | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoenolpyruvate carboxykinase (ATP)
- EC number
- Short namesPCK ; PEP carboxykinase ; PEPCK
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillota > Bacilli > Bacillales > Bacillaceae > Bacillus
Accessions
- Primary accessionA0A2A7GVI7
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length528
- Mass (Da)58,007
- Last updated2017-12-20 v1
- Checksum9690B1389516CFD5