A0A2A4Q357 · A0A2A4Q357_9BACT
- ProteinGlutamate--tRNA ligase
- GenegltX
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids444 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
Catalytic activity
- ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | ATP binding | |
Molecular Function | glutamate-tRNA ligase activity | |
Molecular Function | tRNA binding | |
Molecular Function | zinc ion binding | |
Biological Process | glutamyl-tRNA aminoacylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlutamate--tRNA ligase
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageBacteria > Candidatus Kaiserbacteria
Accessions
- Primary accessionA0A2A4Q357
Proteomes
Subcellular Location
Interaction
Subunit
Monomer.
Structure
Family & Domains
Features
Showing features for motif, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 11-21 | 'HIGH' region | ||||
Sequence: PSPTGKLHIGN | ||||||
Domain | 104-276 | Glutamyl/glutaminyl-tRNA synthetase class Ib catalytic | ||||
Sequence: EGEKGANVIRFRNPNKEITFTDAVRGEITIDTTDFGDFVIARSKTNPIYHLTVVVDDIDMGITHVIRGEDHITSTPRQILLIEALGGTVPSYAHLPLIIGSDKKKLSKRHGAVTYQEFEELGYIPAGVLNYLALLGWNPGDEREFFTKEELIKEFSLERVNNSPAAFSYEKFD | ||||||
Motif | 208-212 | 'KMSKS' region | ||||
Sequence: KLSKR | ||||||
Domain | 319-440 | Aminoacyl-tRNA synthetase class I anticodon-binding | ||||
Sequence: QQVIRERIHKFSDVTTMLEEGEFDWLLATPKPAAEDIIWKETXPETIAKHLKYVQETLENASKWSPEDLKELLWPYADENGRGEVLWPMRFSLTGAKKSPDPFMVAYLLGKEVTLERLNQAI |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length444
- Mass (Da)50,931
- Last updated2017-12-20 v1
- Checksum3E6D62153E43164A