A0A2A4JAM7 · A0A2A4JAM7_HELVI
- ProteinGlycerol-3-phosphate dehydrogenase [NAD(+)]
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids364 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- NAD+ + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H+ + NADH
Pathway
Lipid metabolism.
Phospholipid metabolism; alpha-glycerophosphate cycle.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 14-19 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: GSGNWG | ||||||
Binding site | 101 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: F | ||||||
Binding site | 124 | substrate | ||||
Sequence: K | ||||||
Binding site | 158 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: A | ||||||
Active site | 209 | Proton acceptor | ||||
Sequence: K | ||||||
Binding site | 273 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: R | ||||||
Binding site | 273-274 | substrate | ||||
Sequence: RN | ||||||
Binding site | 300 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 302 | NAD+ (UniProtKB | ChEBI) | ||||
Sequence: Q |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | glycerol-3-phosphate dehydrogenase (FAD) complex | |
Molecular Function | glycerol-3-phosphate dehydrogenase (NAD+) activity | |
Molecular Function | NAD binding | |
Molecular Function | protein homodimerization activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | glycerol-3-phosphate catabolic process | |
Biological Process | glycerophospholipid metabolic process | |
Biological Process | NADH oxidation |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycerol-3-phosphate dehydrogenase [NAD(+)]
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Noctuoidea > Noctuidae > Heliothinae > Heliothis
Accessions
- Primary accessionA0A2A4JAM7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 10-177 | Glycerol-3-phosphate dehydrogenase NAD-dependent N-terminal | ||||
Sequence: VCIIGSGNWGSAIAKIVGKNAARLPNFEDRVTMWVYEEMIEGKKLTEIINETHENVKYLPGHKLPPNVVAIPDVVEAAKDADLLIFVVPHQFVRTICSTLLGKIKPTAAALSLIKGFDIAEGGGIDLISHIITRCLKIPCAVLMGANIASEVADEKFCETTIGCRDVM | ||||||
Domain | 198-343 | Glycerol-3-phosphate dehydrogenase NAD-dependent C-terminal | ||||
Sequence: DEDAVEICGALKNIVAVGAGFVDGLGFGDNTKAAVIRLGLMEMIKFVDVFYPGSKLSTFFESCGVADLITTCYGGRNRRVAEAFVKTGRSIKELEDEMLNGQKLQGPITAEEVNHMLANKNMENKFPLFTAVFRICRGELKPSDFI |
Sequence similarities
Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length364
- Mass (Da)39,998
- Last updated2017-12-20 v1
- ChecksumDDC294D94B0F9B2F
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A2A4JBU8 | A0A2A4JBU8_HELVI | B5V51_4446 | 356 |
Keywords
- Technical term