A0A2A4J9P7 · A0A2A4J9P7_HELVI
- ProteinAurora kinase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids291 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 41 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 60 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Binding site | 109-111 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EFA | ||||||
Active site | 156 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 160-161 | ATP (UniProtKB | ChEBI) | ||||
Sequence: EN | ||||||
Binding site | 174 | ATP (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chromosome passenger complex | |
Cellular Component | kinetochore | |
Cellular Component | spindle microtubule | |
Cellular Component | spindle midzone | |
Cellular Component | spindle pole centrosome | |
Molecular Function | ATP binding | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | mitotic spindle organization | |
Biological Process | regulation of cytokinesis |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAurora kinase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Lepidoptera > Glossata > Ditrysia > Noctuoidea > Noctuidae > Heliothinae > Heliothis
Accessions
- Primary accessionA0A2A4J9P7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for cross-link.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Cross-link | 158 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) | ||||
Sequence: K |
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 31-283 | Protein kinase | ||||
Sequence: FELGSPLGQGKFGNVNVAREKKTGYLVAIKTLFKSQIVRSKCERQVMREIEIQSHLKHPNILRLLTWFHDERRIYLVIEFAAGGELYKHLTNSPKGRFPEARAARYIYQVADAVEYCHQHHVIHRDIKPENILVAFSGDLKLADFGWSVHAPSERRKTMCGTLDYLPPEMIKREVYDVSVDHWCIGVLLYEFLVGKPPFESEGQDKTYARILALDMVYPSYVPEGAKDLISSLLRHSSKERLSLDGVKKHYWV |
Sequence similarities
Family and domain databases
Sequence
- Sequence statusComplete
- Length291
- Mass (Da)33,556
- Last updated2017-12-20 v1
- Checksum8E8BB12D5E0D67F6
Keywords
- Technical term