A0A2A3S4L5 · A0A2A3S4L5_9GAMM

Function

function

Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site82S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site112S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site134S-adenosyl-L-methionine (UniProtKB | ChEBI)
Binding site142S-adenosyl-L-methionine (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionRNA binding
Molecular FunctiontRNA (5-carboxymethylaminomethyluridine(34)-2'-O)-methyltransferase activity
Molecular FunctiontRNA (cytidine(34)-2'-O)-methyltransferase activity
Biological Processwobble position cytosine ribose methylation
Biological Processwobble position uridine ribose methylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA (cytidine(34)-2'-O)-methyltransferase
  • EC number
  • Alternative names
    • tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmL

Gene names

    • Name
      trmL
    • ORF names
      A6J60_000105
      , A6J60_013255

Organism names

  • Taxonomic identifier
  • Strain
    • FDAARGOS_221
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Moraxellales > Moraxellaceae > Psychrobacter

Accessions

  • Primary accession
    A0A2A3S4L5

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain3-154tRNA/rRNA methyltransferase SpoU type

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    181
  • Mass (Da)
    20,350
  • Last updated
    2017-12-20 v1
  • Checksum
    1DFBB86F8781934E
MTIHIVLVHPRIPNNTGSAIRLCANTGAQLHLVEPLGFDLEDKKLRRAGLDYHEYANMQVHKDWEQAKQALNQAGCERMVALTTKLSHPFYEYDFAQTDSGDKIENIALVFGSETAGLADDIRADIGEKNWLRLPMLPDSRSLNLANSVSICLYEVWRQQGFVGDEGRSTGYTELTPYDPK

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NWFK02000001
EMBL· GenBank· DDBJ
PNK59446.1
EMBL· GenBank· DDBJ
Genomic DNA
NWFK02000001
EMBL· GenBank· DDBJ
PNK61733.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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