A0A2A2S8P4 · A0A2A2S8P4_9SPHI

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site98Transition state stabilizer
Active site102Proton acceptor
Binding site288Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      CKK33_16580

Organism names

  • Taxonomic identifier
  • Strain
    • MD40
  • Taxonomic lineage
    Bacteria > Bacteroidota > Sphingobacteriia > Sphingobacteriales > Sphingobacteriaceae > Mucilaginibacter

Accessions

  • Primary accession
    A0A2A2S8P4

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link247↔273Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-101)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for compositional bias, region, domain.

Type
IDPosition(s)Description
Compositional bias1-24Polar residues
Region1-29Disordered
Domain135-453Plant heme peroxidase family profile

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    758
  • Mass (Da)
    83,808
  • Last updated
    2017-12-20 v1
  • Checksum
    2AC6A6281D60BCC3
MENNSNDISKCPFHNGTLKHNTAGGGTRNRDWWPNQLKLNVLRQFSELSNPMGEDFNYAEEFKSLDLEAIKKDLHELMTDSQDWWPADFGHYGGLFIRMAWHSAGTYRVTDGRGGAGAGMQRFAPLNSWPDNVSLDKARRLLWPIKQKYGRKISWADLMILTGNVALESMGFKTFGFAGGRADVWEADELVYWGAETTWLGNDERYADGQPGVAAHGVVSSDEDADGNMHDRKLEQPLAAAHMGLIYVNPEGPDGNPDPIMAAKDIRETFGRMAMNDEETVALIAGGHSFGKTHGAASSDHVGKEPEAAGIESQGFGWSNNFGSGKGADTITSGLEVTWTTTPTQWSNNFFENLFNFEWELTKSPGGAHQWVAKTDQHIIPDAYDPEKKHRPTMLTTDLALRFDPAYEKISRRFLEDHEAFSDAFARAWFKLTHRDMGPRALYLGADVPQEELLWQDVIPATDHALVDDADITILKAKILTSSLTISELVGTAWASASTFRGSDKRGGANGARIRLAPQRYWQVNNPAQLQKVLNVLEGIQHNFNGAQSDGKKISLADLIILAGNAAIEKAAKDAGHDVTVPFTPGRGDATQEQTDVESFGYLEPQADGFRNYRKGRSKASTEEMLIDKAQLLTLTAPELTVLMGGLKVLNINYDGSNHGVFTSRPGQLTNDWFVNLLDMGTEWKAASQDKETYAGNDRATGQTKWTGTRADLVFGSNSELRAIAEVYAAADAEQKFIKDFVATWTKITNLDRFDIKK

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias1-24Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NRSW01000001
EMBL· GenBank· DDBJ
PAW95025.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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