A0A292ZET8 · A0A292ZET8_SPHSA

Function

function

Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

Catalytic activity

Pathway

Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.

Features

Showing features for active site, binding site.

129920406080100120140160180200220240260280
Type
IDPosition(s)Description
Active site26
Binding site113-123ATP (UniProtKB | ChEBI)
Active site155

GO annotations

AspectTerm
Molecular Function4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity
Molecular FunctionATP binding
Biological Processisopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway
Biological Processphosphorylation
Biological Processterpenoid biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
  • EC number
  • Short names
    CMK
  • Alternative names
    • 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase

Gene names

    • Name
      ispE
    • ORF names
      H5V43_06010
      , SFOMI_1895

Organism names

Accessions

  • Primary accession
    A0A292ZET8

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain105-160GHMP kinase N-terminal
Domain227-286GHMP kinase C-terminal

Sequence similarities

Belongs to the GHMP kinase family. IspE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    299
  • Mass (Da)
    31,252
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    ECBBB247ADC32BBA15ED7A32EE526BE3
MPHVEAEDVAARPVDAGELVETAFAKINLALHVRGKRADGYHALESLFVFTELGDRLTGRIRADGEIRLEMDGPFGPLLDGGPDNLVVKAARALQAHLGGSPGADLRLTKILPVASGIGGGSADAAAALRLLTRLWNAPMAPQALERIALSLGSDVPACIGSIPQMVRGRGEILQPQAVEGLTAMPILLVNPGVALSTAEVFGLWDRLDRGPLAAEGLEQLIIEGRNDLEQAAMAAAPVVADVLAALGACAGARLVRMSGSGATCFALFDRDRQMAEAAAVLRAGWNGWWVAETRIRAA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BEWI01000031
EMBL· GenBank· DDBJ
GAY21355.1
EMBL· GenBank· DDBJ
Genomic DNA
CP060035
EMBL· GenBank· DDBJ
QOT72671.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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