A0A292ZET8 · A0A292ZET8_SPHSA
- Protein4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
- GeneispE
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids299 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.
Catalytic activity
- 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + H+
Pathway
Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via DXP pathway; isopentenyl diphosphate from 1-deoxy-D-xylulose 5-phosphate: step 3/6.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 26 | ||||
Binding site | 113-123 | ATP (UniProtKB | ChEBI) | |||
Active site | 155 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity | |
Molecular Function | ATP binding | |
Biological Process | isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway | |
Biological Process | phosphorylation | |
Biological Process | terpenoid biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name4-diphosphocytidyl-2-C-methyl-D-erythritol kinase
- EC number
- Short namesCMK
- Alternative names
Gene names
Organism names
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A292ZET8
Proteomes
Structure
Family & Domains
Sequence
- Sequence statusComplete
- Length299
- Mass (Da)31,252
- Last updated2017-12-20 v1
- MD5 ChecksumECBBB247ADC32BBA15ED7A32EE526BE3
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BEWI01000031 EMBL· GenBank· DDBJ | GAY21355.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP060035 EMBL· GenBank· DDBJ | QOT72671.1 EMBL· GenBank· DDBJ | Genomic DNA |