A0A292Z9I0 · A0A292Z9I0_SPHSA

Function

function

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

Catalytic activity

  • Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
    EC:3.1.26.5 (UniProtKB | ENZYME | Rhea)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentribonuclease P complex
Molecular Function3'-tRNA processing endoribonuclease activity
Molecular Functionribonuclease P activity
Molecular FunctiontRNA binding
Biological ProcesstRNA 5'-leader removal

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Ribonuclease P protein component
  • EC number
  • Short names
    RNase P protein
    ; RNaseP protein
  • Alternative names
    • Protein C5

Gene names

    • Name
      rnpA
    • ORF names
      H5V43_16005
      , SFOMI_0166

Organism names

Accessions

  • Primary accession
    A0A292Z9I0

Proteomes

Subcellular Location

Interaction

Subunit

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.

Family & Domains

Features

Showing features for compositional bias, region.

Type
IDPosition(s)Description
Compositional bias101-124Basic and acidic residues
Region101-162Disordered

Sequence similarities

Belongs to the RnpA family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    162
  • Mass (Da)
    17,946
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    4254F446C8A5654F1716E6116AACAB3D
MTRRADFLAANRGRRTPMPGFVLLVRERGDGDPAMRYGITVTKKIGGAVIRNRMKRRFRVLARDLLPAHGIAGADHVLIGRAEGIERDFGLLRRELEKALGKVMSRPVDEAPRRKGRPSPPKDTAPLRRQEPGFEVATEGSGGTGFPPSQEHGRGRHGRDRP

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias101-124Basic and acidic residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BEWI01000030
EMBL· GenBank· DDBJ
GAY19646.1
EMBL· GenBank· DDBJ
Genomic DNA
CP060035
EMBL· GenBank· DDBJ
QOT71553.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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