A0A292YT41 · A0A292YT41_9PSEU
- Proteinassimilatory sulfite reductase (ferredoxin)
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids840 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors.
Catalytic activity
- hydrogen sulfide + 6 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O = sulfite + 6 reduced [2Fe-2S]-[ferredoxin] + 7 H+
Cofactor
Protein has several cofactor binding sites:
Note: Binds 1 [4Fe-4S] cluster per subunit.
Note: Binds 1 siroheme per subunit.
Pathway
Nitrogen metabolism; nitrate reduction (assimilation).
Features
Showing features for binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 634 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 640 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 674 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 678 | [4Fe-4S] cluster (UniProtKB | ChEBI) | ||||
Sequence: C | ||||||
Binding site | 678 | Fe (UniProtKB | ChEBI) of siroheme (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: C |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 4 iron, 4 sulfur cluster binding | |
Molecular Function | flavin adenine dinucleotide binding | |
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Molecular Function | NADP binding | |
Molecular Function | nitrite reductase activity | |
Molecular Function | sulfite reductase (ferredoxin) activity | |
Biological Process | nitrate assimilation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameassimilatory sulfite reductase (ferredoxin)
- EC number
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Pseudonocardiales > Pseudonocardiaceae > Pseudonocardia
Accessions
- Primary accessionA0A292YT41
Proteomes
PTM/Processing
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-289 | FAD/NAD(P)-binding | ||||
Sequence: ELVVVGHGMVGHRLVAALRDRDTDGTWHVTVLGEEDRPAYDRVALSSYVDGRTEDDLSLGTHDDPLVDVRRATSVVGIDREACEVRIATGETIGYDALVLATGSVPFVPPVPGRDLLGCFVYRTLDDLDAITAAAEAAMARPGPGRRSAVVVGGGLLGLEAARAMRLLGLSPHVVEIAPRLMPVQVDEGGGALLRSLVERQDIAVRCGVSVTGIADDRGRLVAQLSDGVELDADLVVFSAGIRAADGLARATGLAVGERGGVLVDDRCRTADEHVWAVGECAALEG | ||||||
Domain | 324-390 | NADH-rubredoxin oxidoreductase C-terminal | ||||
Sequence: STQLKLLGVDVASFGDAHATTEGALPVVINDPVAGTYAKLVVSDDAATLLGGVLVGDASRYAALRPL | ||||||
Domain | 421-467 | BFD-like [2Fe-2S]-binding | ||||
Sequence: VCSCNAVTKGALRSAVAEGAHTVGALKACTRAGTSCGSCVPLLKSIL | ||||||
Domain | 553-614 | Nitrite/Sulfite reductase ferredoxin-like | ||||
Sequence: QRDGTYSVVPRVPGGEITPDGLIVIGEVARDFGLYTKITGGQRIDMFGARVEQLPAIWRRLV | ||||||
Domain | 625-761 | Nitrite/sulphite reductase 4Fe-4S | ||||
Sequence: GKALRTVKSCVGTTWCRFGQQDSVGLAVELELRYRGLRSPHKIKSGVSGCARECAEARSKDFGIIATETGWNLYVGGNGGFTPRHADLLVSDVDTETLVRLVDRFLMFYVRTADRLQRTAPWIEAMEGGLDHLRAVI |
Sequence similarities
Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length840
- Mass (Da)88,045
- Last updated2017-12-20 v1
- Checksum5075BC0AF73F4B0C