A0A292IHL4 · A0A292IHL4_9MOLU

Function

function

Catalyzes the conversion of lactate to pyruvate.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Features

Showing features for binding site, active site.

131320406080100120140160180200220240260280300
TypeIDPosition(s)Description
Binding site11-16NAD+ (UniProtKB | ChEBI)
Binding site15NAD+ (UniProtKB | ChEBI)
Binding site36NAD+ (UniProtKB | ChEBI)
Binding site67NAD+ (UniProtKB | ChEBI)
Binding site81-82NAD+ (UniProtKB | ChEBI)
Binding site84substrate
Binding site90substrate
Binding site97NAD+ (UniProtKB | ChEBI)
Binding site120-122NAD+ (UniProtKB | ChEBI)
Binding site122-125substrate
Binding site145NAD+ (UniProtKB | ChEBI)
Binding site150-153substrate
Active site177Proton acceptor
Binding site231substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionL-lactate dehydrogenase activity
Biological Processglycolytic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    L-lactate dehydrogenase
  • EC number
  • Short names
    L-LDH

Gene names

    • Name
      ldh
    • ORF names
      MAMA39_00470

Organism names

Accessions

  • Primary accession
    A0A292IHL4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue222Phosphotyrosine

Keywords

Interaction

Subunit

Homotetramer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-144Lactate/malate dehydrogenase N-terminal
Domain147-310Lactate/malate dehydrogenase C-terminal

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    34,416
  • Last updated
    2017-12-20 v1
  • Checksum
    15828BADA42B0A13
MTKDVKVVLIGSGNVGSSFLYAAINQGLSRSYGIIDINSTLRDAQVLDFEDSAWNNPVDFKIHAANYADLKNTEYLVITAGLPQKPGQTRLELAGANVKIMKEIARQVKESGFSGYTIIASNPLDVMTYTYLKTTGFPKNKVIGSGTTLDTARLRSFISRRMNVSNNSVQAFILGEHGDSSVTLFSQIKIDGIPFKNFENIHGINENNYETLLETPVRQKAYEIIKGKGSTYYGIGSALAYILKALINGTDEILPVCAYLDGEYGIHDVCVGVPSIVGKDGIAKVIEYPMNDKELKKFHASVDIIKKYNQEHV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
HG937516
EMBL· GenBank· DDBJ
CDN40173.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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