A0A291MVS5 · A0A291MVS5_SPHYA
- ProteinNADH:ubiquinone reductase (H(+)-translocating)
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids698 (go to sequence)
- Protein existencePredicted
- Annotation score2/5
Function
Catalytic activity
- a ubiquinone + 5 H+(in) + NADH = a ubiquinol + 4 H+(out) + NAD+
a ubiquinone RHEA-COMP:9565 + 5 H+ (in)CHEBI:15378+ CHEBI:57945 = a ubiquinol RHEA-COMP:9566 + 4 H+ (out)CHEBI:15378+ CHEBI:57540
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | respirasome | |
Molecular Function | NADH dehydrogenase (ubiquinone) activity | |
Biological Process | ATP synthesis coupled electron transport |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADH:ubiquinone reductase (H(+)-translocating)
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingobium
Accessions
- Primary accessionA0A291MVS5
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Mitochondrion inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 34-51 | Helical | ||||
Sequence: GALFAACAMSWPIFISFL | ||||||
Transmembrane | 83-102 | Helical | ||||
Sequence: TAVMLVVITSVSSLVHLYSW | ||||||
Transmembrane | 114-132 | Helical | ||||
Sequence: FFAYLSLFTFAMLMLVTAN | ||||||
Transmembrane | 138-156 | Helical | ||||
Sequence: FFGWEGVGLASYLLIGFWF | ||||||
Transmembrane | 177-199 | Helical | ||||
Sequence: LGFMMGIFGTYLVFNTISIPEIL | ||||||
Transmembrane | 219-244 | Helical | ||||
Sequence: TMTVLCLLLFIGAMGKSAQLGLHTWL | ||||||
Transmembrane | 256-278 | Helical | ||||
Sequence: ALIHAATMVTAGVFMVCRLSPMF | ||||||
Transmembrane | 284-305 | Helical | ||||
Sequence: ALTVVTYVGAATCLFAATVGTV | ||||||
Transmembrane | 312-334 | Helical | ||||
Sequence: VIAYSTCSQLGYMFFAAGCGAYG | ||||||
Transmembrane | 340-360 | Helical | ||||
Sequence: LFTHAFFKALLFLGAGSVIHA | ||||||
Transmembrane | 381-407 | Helical | ||||
Sequence: FWTMTLGTLAITGVGLPLVGVGFAGFY | ||||||
Transmembrane | 427-450 | Helical | ||||
Sequence: YYVGVFAALLTSFYSWRLVFLTFF | ||||||
Transmembrane | 521-541 | Helical | ||||
Sequence: LVMLIPLLVLSLGAVFAGFVF | ||||||
Transmembrane | 575-595 | Helical | ||||
Sequence: WVKFGPFTVMLTGLVIAWLAY | ||||||
Transmembrane | 677-696 | Helical | ||||
Sequence: LYTYALVMLIGLAAAATWAM |
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 65-115 | NADH-Ubiquinone oxidoreductase (complex I) chain 5 N-terminal | ||||
Sequence: WIESGSFDAQWALRVDTMTAVMLVVITSVSSLVHLYSWGYMDEEPDQPRFF | ||||||
Domain | 131-422 | NADH:quinone oxidoreductase/Mrp antiporter membrane subunit | ||||
Sequence: ANNLLQMFFGWEGVGLASYLLIGFWFRKPSANAAAIKAFVVNRVGDLGFMMGIFGTYLVFNTISIPEILEMAPSMAGSTIGFLGHRFDTMTVLCLLLFIGAMGKSAQLGLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVCRLSPMFEMSPTALTVVTYVGAATCLFAATVGTVQTDIKRVIAYSTCSQLGYMFFAAGCGAYGAAMFHLFTHAFFKALLFLGAGSVIHAMHHEQDMRYYGGLRKKIPVTFWTMTLGTLAITGVGLPLVGVGFAGFYSKDGILEAAFASGGA | ||||||
Region | 466-511 | Disordered | ||||
Sequence: HDSHGHDDHGHGHDDHAHAGHGHDDHAHAHADHGHDHHAHDAGDGT | ||||||
Domain | 572-688 | NADH dehydrogenase subunit 5 C-terminal | ||||
Sequence: VPTWVKFGPFTVMLTGLVIAWLAYIKNTDWPQRFVATFGALHQFLLNKWYFDELYNFLFVKPAFAIGRFFWQFGDVGFIDRFGPNGLAALVVQGNKITRRLQSGYLYTYALVMLIGL |
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length698
- Mass (Da)76,144
- Last updated2017-12-20 v1
- Checksum43020E529825EDC1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
CP023741 EMBL· GenBank· DDBJ | ATI79219.1 EMBL· GenBank· DDBJ | Genomic DNA |