A0A286QW42 · A0A286QW42_ZIKV
- ProteinGenome polyprotein
- GeneGP1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids3423 (go to sequence)
- Protein existencePredicted
- Annotation score5/5
Function
Catalytic activity
- ATP + H2O = ADP + phosphate + H+
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 1553 | Charge relay system; for serine protease NS3 activity | |||
Active site | 1577 | Charge relay system; for serine protease NS3 activity | |||
Active site | 1637 | Charge relay system; for serine protease NS3 activity | |||
Binding site | 2576 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2606 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2607 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2624 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2625 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2651 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2652 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2740 | S-adenosyl-L-methionine (UniProtKB | ChEBI) | |||
Binding site | 2959 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2963 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2968 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 2971 | Zn2+ 1 (UniProtKB | ChEBI) | |||
Binding site | 3234 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 3250 | Zn2+ 2 (UniProtKB | ChEBI) | |||
Binding site | 3369 | Zn2+ 2 (UniProtKB | ChEBI) | |||
GO annotations
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameGenome polyprotein
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageViruses > Riboviria > Orthornavirae > Kitrinoviricota > Flasuviricetes > Amarillovirales > Flaviviridae > Orthoflavivirus > Orthoflavivirus zikaense
- Virus hosts
Accessions
- Primary accessionA0A286QW42
Subcellular Location
UniProt Annotation
GO Annotation
Host endoplasmic reticulum membrane ; Multi-pass membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Host endoplasmic reticulum membrane ; Peripheral membrane protein
Virion membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 35-58 | Helical | |||
Transmembrane | 746-767 | Helical | |||
Transmembrane | 773-798 | Helical | |||
Transmembrane | 1178-1197 | Helical | |||
Transmembrane | 1273-1290 | Helical | |||
Transmembrane | 1343-1366 | Helical | |||
Transmembrane | 1378-1394 | Helical | |||
Transmembrane | 1400-1417 | Helical | |||
Transmembrane | 1473-1496 | Helical | |||
Transmembrane | 2174-2192 | Helical | |||
Transmembrane | 2199-2216 | Helical | |||
Transmembrane | 2222-2241 | Helical | |||
Transmembrane | 2253-2275 | Helical | |||
Transmembrane | 2306-2327 | Helical | |||
Transmembrane | 2334-2353 | Helical | |||
Transmembrane | 2373-2392 | Helical | |||
Transmembrane | 2442-2462 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Disulfide bond | 293↔320 | ||||
Disulfide bond | 350↔406 | ||||
Disulfide bond | 364↔395 | ||||
Disulfide bond | 382↔411 | ||||
Disulfide bond | 480↔581 | ||||
Disulfide bond | 598↔629 | ||||
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 1373-1502 | Flavivirus NS2B | |||
Domain | 1503-1680 | Peptidase S7 | |||
Domain | 1683-1839 | Helicase ATP-binding | |||
Domain | 1834-2013 | Helicase C-terminal | |||
Domain | 2521-2785 | MRNA cap 0-1 NS5-type MT | |||
Domain | 3049-3199 | RdRp catalytic | |||
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length3,423
- Mass (Da)379,169
- Last updated2017-11-22 v1
- MD5 Checksum4DD134CCD1E1B32C931C399C77A664B7
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MF574571 EMBL· GenBank· DDBJ | ASU55409.1 EMBL· GenBank· DDBJ | Genomic RNA |