A0A285NN65 · A0A285NN65_9AQUI

  • Protein
    Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
  • Gene
    trmFO
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site8-13FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functionflavin adenine dinucleotide binding
Molecular FunctiontRNA (uracil(54)-C5)-methyltransferase activity, 5,10-methylenetetrahydrofolate-dependent
Biological ProcesstRNA methylation
Biological ProcesstRNA wobble uridine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO
  • EC number
  • Alternative names
    • Folate-dependent tRNA (uracil-5-)-methyltransferase
    • Folate-dependent tRNA(M-5-U54)-methyltransferase

Gene names

    • Name
      trmFO
    • ORF names
      SAMN06265353_0016

Organism names

Accessions

  • Primary accession
    A0A285NN65

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-366MnmG N-terminal

Sequence similarities

Belongs to the MnmG family. TrmFO subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    442
  • Mass (Da)
    49,480
  • Last updated
    2017-11-22 v1
  • Checksum
    6EDF56087A1DF353
MERVIVIGAGLAGSEAAYRLAEEGFPVVLYEMRPKRQTPAHKTDKFAELVCSNTLGSMEITSGSGLLKAEMELLGSLTLSAGRHAYVPAGSALGVDRNIFSEYITQKLLSHPNIQVIREEVKKIPRDEVVIVATGPLTSEELSEDIKELIGQDYLFFYDAISPIVEAESVDFTKGFWGSRYGKGGEEDYFNCTLTEEEYKVFYEELLKAQKVVPKDFEKAVYFEGCMPIEELARRGFKTLLFGPMKPVGLKAPDGKTPFAVVQLRKENKEGTLLSLVGFQTQMTYSEQKRVLRLIPCLRNAVFVRLGSMHRNTFIQSNKVLTPFLDMRKMENIFFAGQITGVEGYVASAATGIVAGINAGRLLRGERLLRFPEETMIGALINYITTKEGQLEPMSPVMGLLPPLEEKVKDKALRKKLLAERSLRVLKNFLEEFSLSEKEVKY

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
OBEN01000001
EMBL· GenBank· DDBJ
SNZ10668.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
Help