A0A284S779 · A0A284S779_ARMOS

Function

function

Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

Catalytic activity

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Molecular Functioncarboxylic ester hydrolase activity
Biological Processlipid metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Acyl-protein thioesterase 1
  • EC number
  • Alternative names
    • Palmitoyl-protein hydrolase

Gene names

    • ORF names
      ARMOST_20391

Organism names

  • Taxonomic identifier
  • Strain
    • C18/9
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Agaricomycetidae > Agaricales > Marasmiineae > Physalacriaceae > Armillaria

Accessions

  • Primary accession
    A0A284S779

Proteomes

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, domain.

TypeIDPosition(s)Description
Region237-267Disordered
Domain424-470Phospholipase/carboxylesterase/thioesterase
Domain476-562Phospholipase/carboxylesterase/thioesterase

Sequence similarities

Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    616
  • Mass (Da)
    67,462
  • Last updated
    2017-11-22 v1
  • Checksum
    0F7554B7E1401039
MDASPSPLTLTTRAPISGGSIAAKDEEQAGVAYSQPMVYGWDGIDWSDFESFCIRVLAREESLPDQGSQSYTICVPHLCSLFSRVLSFQHPECFAMDEELQISDSPLPAFIELGPEWGSSDPSDEVDLLPEAIPRNTVVKDECIGGTWHSKIDDPDRYLSLSTSTLQVELSTSYPTPPRSLSPPLSISPVHTYVPARQPTAVAGSSTWASYSEASNVPSPLARNPYRALMFKDVETPSTWGSSSKNNRQRQGGKAPQLDSSRSSPWRRANPYPAMYCLQPERLSNTQILNNPEFLKAISKTCIRKLAAGTHIYVPIKTAKVAKKIAPLYDQNFDFAKTFFGLQRVAPPPDALHPCPYPSCLAALSIEDFLEHYDADHSHWSYSACQKGSCPSFYRPHDPNGKHEVFSLSTYGFLMAQELDCQTVLAKSKHSATIIFLHGLGSSANNIGRLARSIAADPGLHHIKWIMPQAYNVGGDGPEDEEGVNQSMKSLSQIVAQERDNGIESVLFGGFSQGACMSLFMGLTLEDLRIAGIMMLSGKMVLPDKMIEDITPRTKNIPALKGAGFRITENTNAAGGISYHLYQGLAHSVDLSQEVDDLKDWLKKNVPEDPIAQSSG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
FUEG01000038
EMBL· GenBank· DDBJ
SJL16861.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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