A0A270BBN8 · A0A270BBN8_9SPHN
- ProteinNADPH-dependent 7-cyano-7-deazaguanine reductase
- GenequeF
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids156 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
Catalytic activity
- 7-aminomethyl-7-carbaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 2 NADPH + 3 H+
Pathway
tRNA modification; tRNA-queuosine biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 54 | Thioimide intermediate | |||
Active site | 61 | Proton donor | |||
Binding site | 76-78 | substrate | |||
Binding site | 95-96 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | preQ1 synthase activity | |
Biological Process | queuosine biosynthetic process | |
Biological Process | tRNA modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameNADPH-dependent 7-cyano-7-deazaguanine reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingopyxis
Accessions
- Primary accessionA0A270BBN8
Proteomes
Subcellular Location
Structure
Sequence
- Sequence statusComplete
- Length156
- Mass (Da)17,189
- Last updated2017-12-20 v1
- MD5 ChecksumE647339DDCEB6FC37FD4067E9C57319D
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NIWD01000008 EMBL· GenBank· DDBJ | PAL22432.1 EMBL· GenBank· DDBJ | Genomic DNA |