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A0A270BBN8 · A0A270BBN8_9SPHN

  • Protein
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • Gene
    queF
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Pathway

tRNA modification; tRNA-queuosine biosynthesis.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site54Thioimide intermediate
Active site61Proton donor
Binding site76-78substrate
Binding site95-96substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionpreQ1 synthase activity
Biological Processqueuosine biosynthetic process
Biological ProcesstRNA modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NADPH-dependent 7-cyano-7-deazaguanine reductase
  • EC number
  • Alternative names
    • 7-cyano-7-carbaguanine reductase
    • NADPH-dependent nitrile oxidoreductase
    • PreQ(0) reductase

Gene names

    • Name
      queF
    • ORF names
      CD928_10040

Organism names

  • Taxonomic identifier
  • Strain
    • GW247-27LB
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingopyxis

Accessions

  • Primary accession
    A0A270BBN8

Proteomes

Subcellular Location

Keywords

Family & Domains

Features

Showing features for region.

TypeIDPosition(s)Description
Region1-20Disordered

Sequence similarities

Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    156
  • Mass (Da)
    17,189
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    E647339DDCEB6FC37FD4067E9C57319D
MSDSSHPPLAPKHLGQSSELPASPEAAVLDYVPNPRGGELYLVRFAAPEFTSLCPVTGQPDFAHLVIDYAPGETIVESKSLKLFLSSFRNHAGFHEDCTVGIGRRLFDEMQPRWLRIGGYWYPRGGIPIDVFWQSGPPPADLWLPDQGVAAYRGRG

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NIWD01000008
EMBL· GenBank· DDBJ
PAL22432.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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