A0A270B5Q4 · A0A270B5Q4_9SPHN
- ProteinAquaporin Z
- GeneaqpZ
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids241 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity.
Catalytic activity
- H2O(in) = H2O(out)
Features
Showing features for site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 22 | Involved in tetramerization or stability of the tetramer | |||
Site | 45 | Selectivity filter | |||
Site | 176 | Selectivity filter | |||
Site | 185 | Selectivity filter | |||
Site | 191 | Selectivity filter | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | water channel activity |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameAquaporin Z
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Sphingomonadales > Sphingomonadaceae > Sphingopyxis
Accessions
- Primary accessionA0A270B5Q4
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 7-30 | Helical | |||
Transmembrane | 36-56 | Helical | |||
Transmembrane | 83-105 | Helical | |||
Transmembrane | 133-151 | Helical | |||
Transmembrane | 163-183 | Helical | |||
Transmembrane | 203-225 | Helical | |||
Keywords
- Cellular component
Interaction
Subunit
Homotetramer.
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Motif | 65-67 | NPA 1 | |||
Motif | 188-190 | NPA 2 | |||
Domain
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
Sequence similarities
Belongs to the MIP/aquaporin (TC 1.A.8) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length241
- Mass (Da)24,816
- Last updated2017-12-20 v1
- MD5 ChecksumE27D85D01331A7E404BA2D470892C02B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NIWD01000013 EMBL· GenBank· DDBJ | PAL20357.1 EMBL· GenBank· DDBJ | Genomic DNA |