A0A263NW34 · A0A263NW34_9PSED

  • Protein
    Type III pantothenate kinase
  • Gene
    coaX
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
K+ (UniProtKB | Rhea| CHEBI:29103 )

NH4+ (UniProtKB | Rhea| CHEBI:28938 )

K+ (UniProtKB | Rhea| CHEBI:29103 )

Note: A monovalent cation. Ammonium or potassium.

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site6-13ATP (UniProtKB | ChEBI)
Binding site93substrate
Binding site100-103substrate
Active site102Proton acceptor
Binding site122K+ (UniProtKB | ChEBI)
Binding site125ATP (UniProtKB | ChEBI)
Binding site181substrate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionpantothenate kinase activity
Biological Processcoenzyme A biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Type III pantothenate kinase
  • EC number
  • Alternative names
    • PanK-III
    • Pantothenic acid kinase

Gene names

    • Name
      coaX
    • ORF names
      B7453_10725

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • IB20
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A263NW34

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the type III pantothenate kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    249
  • Mass (Da)
    26,768
  • Last updated
    2017-12-20 v1
  • Checksum
    41B1B67A684A998A
MILELDCGNSFIKWRVLGSAIASASAEGIVGSDLALIESLIAIPGLLLTRCRLVSVRASEETGKLVEALQEAFGVTVSCAAPAREMAGVRNGYEEFERLGLDRWLAMLGGFKLASGNCLVLDFGTAATADFIATDGEHLGGFICPGMPLMRSQLRTHTRKIRYDDAAAEQAMERLSPGRTTVEAVERGCTLMLRGFVLTQLELARRYWGDDFTVFLTGGDADLVSDAVPQARFVPDLVFVGLAMACPLS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NMRE01000019
EMBL· GenBank· DDBJ
OZO04599.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp