A0A257K795 · A0A257K795_9FLAO

Function

function

Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
    EC:2.7.13.3 (UniProtKB | ENZYME | Rhea)

Cofactor

[4Fe-4S] cluster (UniProtKB | Rhea| CHEBI:49883 )

GO annotations

AspectTerm
Cellular Componentcytoplasm
Cellular Componentmembrane
Molecular Function4 iron, 4 sulfur cluster binding
Molecular Functionmetal ion binding
Molecular Functionphosphorelay sensor kinase activity
Molecular Functionprotein dimerization activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Oxygen sensor histidine kinase NreB
  • EC number
  • Alternative names
    • Nitrogen regulation protein B

Gene names

    • ORF names
      CFE24_12380

Organism names

  • Taxonomic identifier
  • Strain
    • BFFFF2
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Flavobacteriaceae > Flavobacterium

Accessions

  • Primary accession
    A0A257K795

Proteomes

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane336-354Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain.

Type
IDPosition(s)Description
Signal1-25
ChainPRO_501289774026-595Oxygen sensor histidine kinase NreB

Family & Domains

Features

Showing features for coiled coil, domain.

Type
IDPosition(s)Description
Coiled coil308-335
Domain509-595Histidine kinase

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    595
  • Mass (Da)
    68,670
  • Last updated
    2017-12-20 v1
  • Checksum
    3FB568C9584CB21A
MRIKNKIFVFPFKLVVLLATSLSFGQVNKLVAAQQAIEKEDFEQASQLVQKIDTRLFNPMQWADFLVVKGEIAGFNNNEIESFKFLTQAKKKYLQLNAKTKAIDLNSELFYLLYSQDNNPTDPMLFLNEYMQFARSNKDTLRLARGYQLQACWYVNDPDKKDYCLKLFHQALRFNRIAKDEKLQSTIYNNLSVFFNENLKRPDSALIYLKRDQVYLEKNSKNDELCFNFINQADSYTKKKAYKQAIQCLLKADQIPLKKYPIKTKAILFFCLSENYACCKQYKEAYTYHCLFTKKDSILNQKAQNISINDIQTKYRTKEKELENLQLKVKNKNKSVWIYSILSAVLIGGVLLYFQFVNLKRARLLALNGKELETQKLETTLKKQEVLVIESLVEGQERERRIMAQELHDNMGSQLAALNLNIGVLKHQLEPLNAPNKAAIDKIELMMVDLYNDVRALAHEKKQGVIVQEGLVPALNKTIQQLSNAQLLTVSLYTFGLYKRIDNSLEIMLFRMLQESLTNIVKHAQATQANLYLTQHPDHLNIMLEDNGIGFTYKSNSKQGMGLLGIEEKVEQLGGQFRVDSTPNNGTTLIFDIPL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKJD01000045
EMBL· GenBank· DDBJ
OYU83224.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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