A0A257CXS8 · A0A257CXS8_9BURK

Function

function

Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for site, active site.

Type
IDPosition(s)Description
Site13Important for substrate specificity
Active site81Proton acceptor
Site82Important for substrate specificity
Site164Important for substrate specificity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctiondTTP diphosphatase activity
Molecular FunctionUTP diphosphatase activity
Biological Processnucleotide metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    dTTP/UTP pyrophosphatase
  • EC number
  • Short names
    dTTPase/UTPase
  • Alternative names
    • Nucleoside triphosphate pyrophosphatase
    • Nucleotide pyrophosphatase
      (Nucleotide PPase
      )

Gene names

    • ORF names
      CFE43_01460

Organism names

Accessions

  • Primary accession
    A0A257CXS8

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the Maf family. YhdE subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    200
  • Mass (Da)
    21,155
  • Last updated
    2017-12-20 v1
  • MD5 Checksum
    70C9FB0A167D6C36E5F6AE73119023F1
MSDFIYLASQSPRRSQLLSQLGVRHEVLLPDSSEDAEGLEVIQGNEAPKRYVQRVTALKLEAALVRLKRRGLPLAPVLCSDTTVALGGTIYGKPENATDAKRMLKELSGHTHRVLTAVAIGDGKRSVAVCSVSQVRFASLTAAEIAAYVATEEPMGKAGAYAVQGRAAAFIAHISGSYSGIMGLPLFETAGALKSLGFDV

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKIK01000001
EMBL· GenBank· DDBJ
OYT94127.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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