A0A252CX90 · A0A252CX90_9NOSO

  • Protein
    Lipoprotein signal peptidase
  • Gene
    lspA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.
    EC:3.4.23.36 (UniProtKB | ENZYME | Rhea)

Pathway

Protein modification; lipoprotein biosynthesis (signal peptide cleavage).

Features

Showing features for active site.

115820406080100120140
TypeIDPosition(s)Description
Active site116
Active site132

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionaspartic-type endopeptidase activity
Biological Processproteolysis

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lipoprotein signal peptidase
  • EC number
  • Alternative names
    • Prolipoprotein signal peptidase
    • Signal peptidase II
      (SPase II
      )

Gene names

    • Name
      lspA
    • ORF names
      BV375_31550

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • 106C
  • Taxonomic lineage
    Bacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Nostocaceae > Nostoc

Accessions

  • Primary accession
    A0A252CX90

Proteomes

Subcellular Location

Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-26Helical
Transmembrane65-86Helical
Transmembrane92-115Helical
Transmembrane122-147Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the peptidase A8 family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    158
  • Mass (Da)
    17,791
  • Last updated
    2017-11-22 v1
  • MD5 Checksum
    8860560CBB81D057D4E5876DFD077B29
MRLKNHLFWLAAFIAFFIDQLTKYWVVQTFKLGQTLPLLQDVFHITYVTNTGAAFSLLTGKVEWLRWLSLGVSLVLIGLALFSPLLNLWDQLGYGLILGGAMGNGIDRFILGYVVDFLDFRLINFAVFNMADSFISIGIVCLLIASLQKTPTSSHRSR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MTAW01000209
EMBL· GenBank· DDBJ
OUL19936.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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