A0A246BB57 · A0A246BB57_9FLAO

Function

function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

a divalent metal cation (UniProtKB | Rhea| CHEBI:60240 )

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site71Proton acceptor
Binding site71-72NAD+ (UniProtKB | ChEBI)
Binding site143-144NAD+ (UniProtKB | ChEBI)
Binding site173NAD+ (UniProtKB | ChEBI)
Binding site184-189NAD+ (UniProtKB | ChEBI)
Binding site208NAD+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular FunctionNAD binding
Molecular FunctionNAD+ kinase activity
Biological ProcessNAD metabolic process
Biological ProcessNADP biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    NAD kinase
  • EC number
  • Alternative names
    • ATP-dependent NAD kinase

Gene names

    • Name
      nadK
    • ORF names
      AP75_03215

Organism names

  • Taxonomic identifier
  • Strain
    • DSM 19056
  • Taxonomic lineage
    Bacteria > Bacteroidota > Flavobacteriia > Flavobacteriales > Weeksellaceae > Chryseobacterium group > Kaistella

Accessions

  • Primary accession
    A0A246BB57

Proteomes

Subcellular Location

Keywords

Family & Domains

Sequence similarities

Belongs to the NAD kinase family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    288
  • Mass (Da)
    32,708
  • Last updated
    2017-10-25 v1
  • MD5 Checksum
    B737A9B034DB204B88684DE98B37C8FF
MKAAIYSQKNDLDTFLYLSKFVSELEKRGVQAVLYDEMANAMQFSKIFETFTRKEDLKEKKVDLFFTFGGDGTIVNSILFVQDLEIPVVGVNTGRLGFLASFSKEEVFLELDEIIRGEVKISRRSVIEVVSPNKSMFFPYALNDITISRKETTAMITVESYINGEFLNVFWGDGVIISTPTGSTAYSLSCGGPIITPNNENFVITPIAPHNLNVRPLILNDDVEIRLKVESRVPQYSLSLDSRLIHMETNVEIVLKKARFQILLVLPNNLSFFETIRQKLLWGKDKRN

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
JASZ02000004
EMBL· GenBank· DDBJ
OWK98881.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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