A0A246AJD8 · A0A246AJD8_9FLAO

Function

function

Catalyzes the reversible phosphorylation of UMP to UDP.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Activity regulation

Inhibited by UTP.

Pathway

Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site9-12ATP (UniProtKB | ChEBI)
Binding site51UMP (UniProtKB | ChEBI)
Binding site52ATP (UniProtKB | ChEBI)
Binding site56ATP (UniProtKB | ChEBI)
Binding site71UMP (UniProtKB | ChEBI)
Binding site132-139UMP (UniProtKB | ChEBI)
Binding site159ATP (UniProtKB | ChEBI)
Binding site165ATP (UniProtKB | ChEBI)
Binding site168ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular FunctionUMP kinase activity
Biological Process'de novo' CTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUDP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Uridylate kinase
  • EC number
  • Short names
    UK
  • Alternative names
    • Uridine monophosphate kinase
      (UMP kinase
      ; UMPK
      )

Gene names

    • Name
      pyrH
    • ORF names
      CBW16_11790

Organism names

Accessions

  • Primary accession
    A0A246AJD8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-213Aspartate/glutamate/uridylate kinase

Sequence similarities

Belongs to the UMP kinase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    235
  • Mass (Da)
    25,658
  • Last updated
    2017-10-25 v1
  • MD5 Checksum
    47CDF1B8739DA23708D3A4811A5E1C39
MKYKRILLKLSGEALMGNRQYGIDNDRLKDYAAEIKKVVDKGCEVAIVIGGGNIFRGLAGAAKGMDRVQGDYMGMLATVINGMALQGALEDAGIYTRLQSAIEMDKVAEPFIKRKATRHLEKGRVVIFGAGTGNPYFTTDTAATLRAIEIGADVILKGTRVDGIYDSDPEINEDAVKFNSLTFDEVFEKGLKVMDMTAFTLSHENKLPIIVFDMNKEGNLLKIVEGETIGTLVNI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NHOS01000004
EMBL· GenBank· DDBJ
OWK72922.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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