A0A243RRY9 · A0A243RRY9_9ACTN

Function

function

Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.

Features

Showing features for site, active site, binding site.

Type
IDPosition(s)Description
Site105Transition state stabilizer
Active site109Proton acceptor
Binding site272Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentcytosol
Molecular Functioncatalase activity
Molecular Functionheme binding
Molecular Functionmetal ion binding
Biological Processcellular response to hydrogen peroxide
Biological Processhydrogen peroxide catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Catalase-peroxidase
  • EC number
  • Short names
    CP
  • Alternative names
    • Peroxidase/catalase

Gene names

    • Name
      katG
    • ORF names
      CA984_09685

Organism names

  • Taxonomic identifier
  • Strain
    • M26
  • Taxonomic lineage
    Bacteria > Actinomycetota > Actinomycetes > Streptosporangiales > Streptosporangiaceae > Streptosporangium

Accessions

  • Primary accession
    A0A243RRY9

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for cross-link.

TypeIDPosition(s)Description
Cross-link231↔257Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-108)

Post-translational modification

Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.

Interaction

Subunit

Homodimer or homotetramer.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region1-37Disordered
Domain142-437Plant heme peroxidase family profile
Region350-378Disordered

Sequence similarities

Belongs to the peroxidase family. Peroxidase/catalase subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    743
  • Mass (Da)
    80,739
  • Last updated
    2017-10-25 v1
  • MD5 Checksum
    3406131279BB3324FD5B013E5FD8797A
MSENHDAIVTDAKTEGGSGCPVAHERASHPTQGGGNRQWWPERLNLKILAKNPAVANPLGEGFDYAEAFKSLDLAAVKRDIAEVLTSSQDWWPADYGHYGPFMVRMAWHSAGTYRISDGRGGAGAGQQRFAPLNSWPDNGNLDKARRLLWPVKKKYGRQLSWADLLILTGNVALESMGFTTFGFAGGREDVWEPEEDVYWGPEFTWLDDQRYTGDRELENPLGAVQMGLIYVNPEGPNGNPDPLAAARDIRETFRRMAMNDEETAALIAGGHTFGKTHGAGPADHVGADPEAAPLEDQGFGWKNTYGTGKGGDTITSGLEGAWTNTPVTWDNSFLEILYGYEWELSKSPAGAHQWKPKDGAGAGTVPDAHDPSKSHAPTMLTTDLALRVDPVYEQITRRWLENPAEFADAFARAWFKLTHRDMGPVVRYLGPEVPAETLLWQDPLPAVTHETVDAADIASLKGQVLASGLSVSQLVSTAWASASSFRGSDKRGGANGARIRLEPQSGWEVNDPDQLATVLRTLEGIQESFNADRTDGKRVSLADLIVLAGGAAVERAAKDAGFDVEVPFTPGRVDASQEQTDVESFAALEPTADGFRNYLGKGNRLPAEYLLIDRANLLTLSAPEMTVLVGGLRVLGANYRQAPLGVLTTTPGTLTNDFFVNLLDLGTTWKATSEDANTFEGRDAATGEVKWTGSRTDLVFGSNSELRALAEVYASDDAKEKFVNDFVAAWHKVMNLDRFDLA

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NGFP01000031
EMBL· GenBank· DDBJ
OUC97785.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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