A0A241XHA2 · A0A241XHA2_PSEAI

  • Protein
    Large ribosomal subunit protein uL2
  • Gene
    rplB
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentlarge ribosomal subunit
Molecular FunctionrRNA binding
Molecular Functionstructural constituent of ribosome
Molecular Functiontransferase activity
Biological Processcytoplasmic translation

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Large ribosomal subunit protein uL2

Gene names

    • Name
      rplB
    • ORF names
      CAZ10_34025
      , CSB93_1987
      , DT376_00175
      , GNQ48_26670
      , GUL26_34505
      , IPC1295_31620
      , L4V69_07055
      , PAERUG_P19_London_7_VIM_2_05_10_03302

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • P19_London_7_VIM_2_05_10
    • S567_C10_BS
    • PA-W36
    • AR_0356
    • B2-305
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Pseudomonadales > Pseudomonadaceae > Pseudomonas

Accessions

  • Primary accession
    A0A241XHA2
  • Secondary accessions
    • A0A1S1C9G7

Proteomes

Subcellular Location

Interaction

Subunit

Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

Family & Domains

Features

Showing features for region, domain.

Type
IDPosition(s)Description
Region34-54Disordered
Domain124-252Large ribosomal subunit protein uL2 C-terminal
Region223-273Disordered

Sequence similarities

Belongs to the universal ribosomal protein uL2 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    273
  • Mass (Da)
    29,579
  • Last updated
    2018-09-12 v1
  • MD5 Checksum
    3A8202FE29993BC194E7292D6F7D4D8E
MAIVKCKPTSAGRRFVVKVVNQELHKGAPYAPLLEKKSKSGGRNNNGRITTRHIGGGHKQHYRLVDFRRNKDGIPAIVERVEYDPNRTAHIALLKYADGERRYIIAPKGVAAGDQLISGIGAPIKAGNSMPLRNIPVGSTVHGIELKPGKGAQIARSAGASAQLVAREGAYVTLRLRSGEMRKVLAECRATLGEVSNSEHSLRSLGKAGATRWRGVRPTVRGVAMNPVDHPHGGGEGRTSAGRHPVSPWGLQTKGKKTRSNKRTDNMIVRRRK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP027169
EMBL· GenBank· DDBJ
AVK02732.1
EMBL· GenBank· DDBJ
Genomic DNA
CVVU01000204
EMBL· GenBank· DDBJ
CRP05944.1
EMBL· GenBank· DDBJ
Genomic DNA
WOAD01000032
EMBL· GenBank· DDBJ
MUI38598.1
EMBL· GenBank· DDBJ
Genomic DNA
WXZT01000048
EMBL· GenBank· DDBJ
MZZ17383.1
EMBL· GenBank· DDBJ
Genomic DNA
NFFZ01000030
EMBL· GenBank· DDBJ
OTI55284.1
EMBL· GenBank· DDBJ
Genomic DNA
QORE01000002
EMBL· GenBank· DDBJ
RCI76832.1
EMBL· GenBank· DDBJ
Genomic DNA
NSNE01000031
EMBL· GenBank· DDBJ
RPM03833.1
EMBL· GenBank· DDBJ
Genomic DNA
CP136986
EMBL· GenBank· DDBJ
WOS78891.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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