A0A240B0T9 · A0A240B0T9_SERFI
- Protein2-hydroxy-3-oxopropionate reductase
- GenegarR_1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids296 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the reduction of tatronate semialdehyde to D-glycerate.
Catalytic activity
- (R)-glycerate + NAD+ = 2-hydroxy-3-oxopropanoate + NADH + H+
Pathway
Carbohydrate acid metabolism; galactarate degradation; D-glycerate from galactarate: step 3/3.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 4-18 | NAD+ (UniProtKB | ChEBI) | |||
Binding site | 95 | NAD+ (UniProtKB | ChEBI) | |||
Active site | 170 | ||||
Binding site | 238 | NAD+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-hydroxy-3-oxopropionate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | galactarate catabolic process | |
Biological Process | glyoxylate metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-hydroxy-3-oxopropionate reductase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Serratia
Accessions
- Primary accessionA0A240B0T9
Proteomes
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 2-161 | 6-phosphogluconate dehydrogenase NADP-binding | |||
Domain | 164-284 | 3-hydroxyisobutyrate dehydrogenase-like NAD-binding | |||
Sequence similarities
Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length296
- Mass (Da)30,783
- Last updated2017-10-25 v1
- MD5 Checksum7263ECE6DD99D7803E230B0712ED28AA
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
LT906479 EMBL· GenBank· DDBJ | SNV88696.1 EMBL· GenBank· DDBJ | Genomic DNA |