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A0A237QZ82 · A0A237QZ82_KLEPN

Function

function

Resistance to Hg2+ in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg0.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Note: Binds 1 FAD per subunit.

Features

Showing features for binding site.

156050100150200250300350400450500550
TypeIDPosition(s)Description
Binding site144FAD (UniProtKB | ChEBI)
Binding site276-283NAD+ (UniProtKB | ChEBI)
Binding site361NAD+ (UniProtKB | ChEBI)
Binding site402FAD (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionflavin adenine dinucleotide binding
Molecular Functionmercury (II) reductase (NADP+) activity
Molecular Functionmercury ion binding
Molecular FunctionNADP binding
Molecular Functionoxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Biological Processdetoxification of mercury ion

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Mercuric reductase
  • EC number
  • Alternative names
    • Hg(II) reductase

Gene names

    • Name
      merA

Encoded on

  • Plasmid pIncAC-KP4898

Organism names

  • Taxonomic identifier
  • Strain
    • KP4898
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Klebsiella/Raoultella group > Klebsiella

Accessions

  • Primary accession
    A0A237QZ82

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond135↔140Redox-active

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain1-64HMA

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    560
  • Mass (Da)
    58,049
  • Last updated
    2017-10-25 v1
  • MD5 Checksum
    1EBE7EB577AB4B7F95E57E0B5FFDAED1
MYLNITGMTCDSCATHVKEALEKVPGVLSALVSYPNGSAQLATDPGTSPEALTAAVAGLGYKATPADAPSTSARGRLLGKALGWLGGDDKAGGDGDGLHVAVIGSGGAAMAAALKAVEQGAKVTLIERGTIGGTCVNVGCVPSKIMIRAAHIAHLRRESPFDSGIAATVPAIDRSKLLAQQQARVDELRHAKYEGILDGNPAITVLHGEARFKDDQRLAVRLNDGGERVVAFDRCLVATGASPAVPLIPGLKESPFWTSTEALVSDTIPERLAVIGSSVVALELAQAFARLGSKVTILARSTLFFREDPAIGEAVTAAFRAEGIEVLEHTQASQVAHVGGEFVLTTGHGEIRADKLLVATGRAPNTRSLALEAAGVAVNAQGAIVIDKGMRTSAPHIYAAGDCTDQPQFVYVAAAAGTRAAINMTGGDAALDLTAMPAVVFTDPQVATVGYSEAEAHHDGIVTDSRTLTLDNVPRALANFDTRGFIKLVIEEGSGRLIGVQAVAPEAGELIQTAVLAIRNRMTVQELADQLFPYLTMVEGLKLAAQTFSKDVKQLSCCAG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KY882285
EMBL· GenBank· DDBJ
ASM79734.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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