A0A232F5Y9 · A0A232F5Y9_9HYME
- ProteinGlycerol-3-phosphate phosphatase
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids308 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism. Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear. In vitro, has also a phosphatase activity toward ADP, ATP, GDP and GTP.
Catalytic activity
- O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate
Cofactor
Note: Divalent metal ions. Mg2+ is the most effective.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 27 | Proton donor | |||
Binding site | 27 | Mg2+ (UniProtKB | ChEBI) | |||
Active site | 29 | Proton donor | |||
Binding site | 29 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 220 | substrate | |||
Binding site | 245 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | metal ion binding | |
Molecular Function | phosphatase activity |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGlycerol-3-phosphate phosphatase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Endopterygota > Hymenoptera > Apocrita > Proctotrupomorpha > Chalcidoidea > Pteromalidae > Pteromalinae > Trichomalopsis
Accessions
- Primary accessionA0A232F5Y9
Proteomes
Interaction
Structure
Family & Domains
Sequence similarities
Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length308
- Mass (Da)34,271
- Last updated2017-10-25 v1
- MD5 ChecksumB3B2864AC66E1BD0D6644681CE238925
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NNAY01000922 EMBL· GenBank· DDBJ | OXU25893.1 EMBL· GenBank· DDBJ | Genomic DNA |