A0A229Z3R7 · A0A229Z3R7_9EURO

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Ni cation (UniProtKB | Rhea| CHEBI:25516 )

Note: Binds 2 nickel ions per subunit.

Pathway

Nitrogen metabolism; urea degradation; CO2 and NH3 from urea (urease route): step 1/1.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site405Ni2+ 1 (UniProtKB | ChEBI)
Binding site407Ni2+ 1 (UniProtKB | ChEBI)
Binding site488Ni2+ 1 (UniProtKB | ChEBI); via carbamate group
Binding site488Ni2+ 2 (UniProtKB | ChEBI); via carbamate group
Binding site490substrate
Binding site517Ni2+ 2 (UniProtKB | ChEBI)
Binding site543Ni2+ 2 (UniProtKB | ChEBI)
Active site591Proton donor
Binding site631Ni2+ 1 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componenturease complex
Molecular Functionnickel cation binding
Molecular Functionurease activity
Biological Processurea catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Urease
  • EC number
  • Alternative names
    • Urea amidohydrolase

Gene names

    • Name
      URE1
    • ORF names
      CDV55_106565
      , CFD26_105683

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • HMR AF 1038
    • HMR AF 23
  • Taxonomic lineage
    Eukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Aspergillus > Aspergillus subgen. Fumigati

Accessions

  • Primary accession
    A0A229Z3R7

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for modified residue.

TypeIDPosition(s)Description
Modified residue488N6-carboxylysine

Post-translational modification

Carbamylation allows a single lysine to coordinate two nickel ions.

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain400-836Urease

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    836
  • Mass (Da)
    91,013
  • Last updated
    2017-10-25 v1
  • Checksum
    30B9FCB7DD8F0095
MHLIPKELDKLVISQLGFLAQRRLARGVRLNHAEAAALISSNLQELIRDGHYSVADLMSIGKTMLGRRHVLPSVVHTLVELQVEGTFPTGTYLVTVHHPISSDDGDLEKALYGSFLPIPPADTFPDPNPDDYLPEKMPGAVLPVKNERITLNDGRKRIRLKVMSKGDRPIQVGSHYHFIETNPQLHFDRLRAYGYRLDIPAGTSVRFEPGDTKTVTLVEIAGNRIIKGGNFLASGKVDISRAEEIMQRLQAEGFAHVPEPTADSALITPFTMDREAYARMFGPTTGDLVRLGLTNLWVRVEKDCTVYGDECTFGGGKTLREGMGQSSERSEAECLDTVITNALIIDWSGIYKADIGIKNGLISAIGKAGNPDMMDGVHPDMIVGSSTDVIAGENKIVTAGGFDTHIHFICPQQVDEALASGITTFLGGGTGPSTGTNATTCTPGPTHMRQMIQACDSLPINVGITGKGNDCGGKSIEEQIRAGAAGLKLHEDWGSTPAAIDTCLDMCDKFDVQCMIHTDTLNESGFVEQTVKSFKNRTIHTYHTEGAGGGHAPDIISVVEHPNVLPSSTNPTRPFTMNTLDEHLDMLMVCHHLSKNIPEDVAFAESRIRAETIAAEDVLHDLGAISMMSSDSQAMGRCGEVILRTWNTAHKNKAQRGPLQEDEGTGADNFRVKRYISKYTINPAIAQGMSHLIGSVEVGKLADLVIWHPSSFGTKPAQILKSGMIVASQMGDPNGSIPTIEPVIMRPMFGSFVPSTSIMWVSQASIDDGIVQSYGLKKRIEPVRNCRNVGKKDMKFNDTMPKMRVDPESYRVEADGVLCEAEPADSLPLTQDYFVY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NKHV02000071
EMBL· GenBank· DDBJ
RHZ64885.1
EMBL· GenBank· DDBJ
Genomic DNA
NIDN02000026
EMBL· GenBank· DDBJ
RLL99711.1
EMBL· GenBank· DDBJ
Genomic DNA

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Disclaimer

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