A0A229P1J8 · A0A229P1J8_9BACL

  • Protein
    ATP-dependent protease subunit HslV
  • Gene
    hslV
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ATP-dependent cleavage of peptide bonds with broad specificity.
    EC:3.4.25.2 (UniProtKB | ENZYME | Rhea)

Activity regulation

Allosterically activated by HslU binding.

Features

Showing features for active site, binding site.

118020406080100120140160180
TypeIDPosition(s)Description
Active site8
Binding site165Na+ (UniProtKB | ChEBI)
Binding site168Na+ (UniProtKB | ChEBI)
Binding site171Na+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentHslUV protease complex
Cellular Componentproteasome core complex
Molecular Functionmetal ion binding
Molecular Functionthreonine-type endopeptidase activity
Biological Processproteolysis involved in protein catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent protease subunit HslV
  • EC number

Gene names

    • Name
      hslV
    • ORF names
      CGZ75_04535

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • R33
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus

Accessions

  • Primary accession
    A0A229P1J8

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.

Family & Domains

Sequence similarities

Belongs to the peptidase T1B family. HslV subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    180
  • Mass (Da)
    19,318
  • Last updated
    2017-10-25 v1
  • Checksum
    F9773BDA2BFA2ADA
MEMQFHATTICAVRHNGKGAIAGDGQVTFGNSMIMKGSAKKVRRLYRGQVAAGFAGSVADAITLFEKFESKLEEHHGNLQRAAVELAKDWRSDRILRRLEAMLLVMDDSGLLLISGNGEVIEPDDGILAIGSGGSFALAAARALKKHAPDLSAREMAQAALETAAEICVFTNHNIIVEEV

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NMUQ01000001
EMBL· GenBank· DDBJ
OXM15978.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp