A0A225CNF0 · A0A225CNF0_9MICO

Function

function

Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpeptidyl-prolyl cis-trans isomerase activity
Molecular Functionprotein folding chaperone
Molecular Functionribosome binding
Biological Process'de novo' cotranslational protein folding
Biological Processcell division
Biological Processchaperone-mediated protein folding
Biological Processprotein transport
Biological Processprotein unfolding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Trigger factor
  • EC number
  • Short names
    TF
  • Alternative names
    • PPIase

Gene names

    • Name
      tig
    • ORF names
      B5P24_13360

Organism names

Accessions

  • Primary accession
    A0A225CNF0

Proteomes

Subcellular Location

Cytoplasm
Note: About half TF is bound to the ribosome near the polypeptide exit tunnel while the other half is free in the cytoplasm.

Keywords

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain165-211PPIase FKBP-type
Region432-483Disordered

Domain

Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.

Sequence similarities

Belongs to the FKBP-type PPIase family. Tig subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    483
  • Mass (Da)
    52,581
  • Last updated
    2017-10-25 v1
  • Checksum
    BAA741CE73971776
MKTTVEKLSPTRVKLAISATPEDLKPHIDHAYGHIAEQVAIPGFRKGKVPPPIIDQRVGREAVLEHAVNDGMDGFYQAAVKETDIRPLGRPEADVKEWPGKDLTGDLLLEIEVDVRPDFELPAYEGLELTVDSVEVTDDEVGTELDSLRSRFGTLITVDRPAKTGDFVQIDLTATIAGNAVDTASGISYELGSGDLIDGIDEALESLTAGESTTFESKLLGGDNEGETAEIAVTVQSVKERELPEADDDFAQIASEFDTIDELRADLKVQVGKSKVFGQVTQARDQIVDKLLETVEIPVPEKLVEDEVHRHLENENRLEDDVHRAEVKESSEKAFRQQLLLDVIAEKEDLKVSQDELTQYLIQGAQQYNMEPNEFVQVLQQNNQIPAMVGEVARNKALAVVLDKAKVVDADGKVVDVTEFTQPVVRDADAVTEEPADADAEAVVADAPAEEASAPAAEEAPVEKPKKKAAPKKKAAEKAADSE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MZMQ01000001
EMBL· GenBank· DDBJ
OQJ63913.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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