A0A225C5I1 · A0A225C5I1_9MICO
- ProteinCoproporphyrinogen III oxidase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids480 (go to sequence)
- Protein existenceInferred from homology
- Annotation score2/5
Function
function
Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.
Catalytic activity
- coproporphyrinogen III + 3 O2 = coproporphyrin III + 3 H2O2This reaction proceeds in the forward direction.
Cofactor
Pathway
Porphyrin-containing compound metabolism; protoheme biosynthesis.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | oxygen-dependent protoporphyrinogen oxidase activity | |
Biological Process | heme biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCoproporphyrinogen III oxidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Actinomycetota > Actinomycetes > Micrococcales > Microbacteriaceae > Clavibacter
Accessions
- Primary accessionA0A225C5I1
Proteomes
Subcellular Location
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 25-477 | Amine oxidase | ||||
Sequence: GGLIAARACALAGRRVILVEASPALGGTVGSHVVDGLRLDSGAESFATRRGTVAAYLGELGLADRIVQPNPDGAWVQLAERAIQLPRTGLLGIPAHPFDLTIATAIGRVGVVRAKADLALPASVGAKERTLGGLVRARMGDRVVDRLVAPIVSGVHSAHPDEVDADSVAPGLRAGLAEHGSLGRAVASMRAASPAGSAVSGVVGGVHLLVDALVADLQRLGVDVRTSLAVESVHRHRSHEGAAAFDDWHVELADGRGIDAAGVVLAIPAAGLVRLFSGLAPRAVTEGWPEPSSVELVTLVVRAPELDAAPRGTGVLVSADVPDVRAKALTHATAKWPWLKDLAGDRHVLRLSYGRAGGNDDTAAVPDDELTAIAVRDASALLGTDLAGRVTGSARVRWTNALPFAASGHRERVQAVRDEAAEHPGLEITGSAVAGTGLASVVADAVAAADRVL |
Sequence similarities
Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length480
- Mass (Da)48,911
- Last updated2017-10-25 v1
- Checksum7C6311FA1B8B9588