A0A224XIP0 · A0A224XIP0_9HEMI

  • Protein
    ATP-binding cassette sub-family B member 6
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

Catalytic activity

  • heme b(in) + ATP + H2O = heme b(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
    EC:7.6.2.5 (UniProtKB | ENZYME | Rhea)
  • pheophorbide a(in) + ATP + H2O = pheophorbide a(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • protoporphyrin IX(in) + ATP + H2O = protoporphyrin IX(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin I(in) + ATP + H2O = uroporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • uroporphyrin III(in) + ATP + H2O = uroporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin I(in) + ATP + H2O = coproporphyrin I(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrin III(in) + ATP + H2O = coproporphyrin III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • coproporphyrinogen III(in) + ATP + H2O = coproporphyrinogen III(out) + ADP + phosphate + H+
    This reaction proceeds in the forward direction.

GO annotations

AspectTerm
Cellular Componentearly endosome membrane
Cellular Componentextracellular region
Cellular ComponentGolgi membrane
Cellular Componentlysosomal membrane
Cellular Componentmelanosome membrane
Cellular Componentmitochondrial outer membrane
Cellular Componentmultivesicular body membrane
Molecular FunctionABC-type heme transporter activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular Functionheme binding

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-binding cassette sub-family B member 6
  • EC number
  • Alternative names
    • ABC-type heme transporter ABCB6

Organism names

  • Taxonomic identifier
  • Organism
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Arthropoda > Hexapoda > Insecta > Pterygota > Neoptera > Paraneoptera > Hemiptera > Heteroptera > Panheteroptera > Cimicomorpha > Reduviidae > Triatominae > Panstrongylus

Accessions

  • Primary accession
    A0A224XIP0

Subcellular Location

Cell membrane
; Multi-pass membrane protein
Early endosome membrane
Endoplasmic reticulum membrane
; Multi-pass membrane protein
Endosome membrane
; Multi-pass membrane protein
Golgi apparatus membrane
; Multi-pass membrane protein
Late endosome membrane
Lysosome membrane
Melanosome membrane
Mitochondrion outer membrane
; Multi-pass membrane protein
Secreted, extracellular exosome

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane69-89Helical
Transmembrane95-119Helical
Transmembrane131-153Helical
Transmembrane173-191Helical
Transmembrane252-271Helical
Transmembrane369-392Helical
Transmembrane398-418Helical
Transmembrane485-506Helical
Transmembrane518-538Helical

Keywords

PTM/Processing

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain253-543ABC transmembrane type-1
Domain577-811ABC transporter

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    829
  • Mass (Da)
    93,819
  • Last updated
    2017-10-25 v1
  • Checksum
    D766D5E61DEEDACE
MGYCPPGVSFFDIWKDHGISDCFMDTTSTSIISGHLLIFGSAQLWMYNKYGSRISRHSIPPSTLYIVQLLMTIFISVLAIFKFILQAVVLNNGAIYGYMVLSTVFTTLIYPLSAILIIVERNYLLPSVPTRGHGLVLLIFWTLMFISENLMFINLHRSDLWFNLKTWTDKLQMALFVLRYITCLIVFVLGLRAPGILTTRDYLNLTSSTASINGEGLTGPPTTSTWSQFSKKVRILAPFVWPRKSIQLQLRVIFCLALLVAGRFINVYVPIYSKLIVDSMTATPLVFRWDLVLTFAAFKFLQGGGTGGMGCLNNLRQFLWIRVQQYTTKEIEVELFRHLHGLSLRWHLGRKTGEVLRVMDRGTDSINNLLSYILFSILPTISDVGIAVIYFILSFNLWFGIIVFCTMFFYILATIMVTEWRTKFQRKMNLADNARSTRSIDSLLNFETVKYYGAEDFEVTCFSEAVNKFQVEEWKSTASLNLLNTLQNIVVTAGLLGGSMLCVYMVTNNHGLTVGDYVLFASYILQLYVPLNWFGTYYRAIQKNFIDMENMFDLLAEKPEVVDFPAASNLVITQGVVEFRNVHFYYNPDRVILKGVSFYVPQGKTLALVGPSGSGKSTIMRLLFRFYDVVEGEILIDGQNIKHVKQASLRRAIGVVPQDTVLFNNTISFNIQYGRVNAPDVDIVSAAKSADIHEKILTFPESYNTQVGERGLKLSGGEKQRVAIARTILKSPAIVLLDEATSALDTQTERNIQSSLARVCANRTTIVIAHRLSTIIHADEIAVLKDGEIVERGRHEDLIKRGGVYEEMWQQQLRAQSDTNSESKEQEKE

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
GFTR01008116
EMBL· GenBank· DDBJ
JAW08310.1
EMBL· GenBank· DDBJ
Transcribed RNA

Similar Proteins

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