A0A223D348 · A0A223D348_9BACL

  • Protein
    ATP-dependent DNA helicase
  • Gene
    pcrA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

Catalytic activity

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site34-41ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Cellular ComponentDNA helicase complex
Molecular Function3'-5' DNA helicase activity
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionDNA binding
Molecular Functionisomerase activity
Biological ProcessDNA unwinding involved in DNA replication
Biological Processrecombinational repair

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    ATP-dependent DNA helicase
  • EC number

Gene names

    • Name
      pcrA
    • ORF names
      CIG75_13735

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • THMBR28
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Alicyclobacillaceae > Tumebacillus

Accessions

  • Primary accession
    A0A223D348

Proteomes

Subcellular Location

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain13-293UvrD-like helicase ATP-binding
Domain294-567UvrD-like helicase C-terminal

Sequence similarities

Belongs to the helicase family. UvrD subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    709
  • Mass (Da)
    80,653
  • Last updated
    2017-10-25 v1
  • Checksum
    F9768385CA42DA03
MTTRTINPAQIAKGLNPEQKAAVETTEGPLLILAGAGSGKTSVLTRRIAYLLGVRGVSPFNILAITFTNKAAKEMNERVRKLVGDVAEDLWMSTFHSMCVRILRREAERIGYQNNFTILDADDQASAVKQSMLDLNLDIKKFDPSSIQWRISAAKNELLTPDDFVKTAGKKLQDITASQVYRVYQRKLQDFNAMDFDDLIMKTVELFETHPDVLEQYQNKFRYIHVDEYQDTNRAQYKLVKLLATKYRNLCVVGDGDQAIYAWRGADISNILNFEKDYPEATVIKLEQNYRSTSTILDAANAVIRNNTARKDKALWSKKGQGDKISIYTALDQEDEAHYIVQQVKNHKDNGGAYGDCTVLYRANAMSRIVEEAFLQAALPYKILGGMTFYDRREIKDVMAYLKTLANPQDEISLLRIINAPKRSIGPGTIQKLLDYAHDRDLTLLDAMGFPDENGLPVKTAATCKEFHDMMKYLHVCQEGLTVSEYLSEVLEKSGYRQMYAHSSKEEDQMRLENIEEMFSITKSFDRRRGGTVGDFLAEVSLLSDNDKEKGDDGEAVLMMTMHASKGLEFPTVFIIGCEETIFPHMRSMDDIKGIEEERNLAYVGITRAKEKLHMLHCAERTLFGNTQRNDPSRFLDEIPEEYLDRTVGYVESDIVWKSGDMLKHPQWGQGMVLDKRGEDETLELTVMFHPSIGEKKVLPRFTRLDKIG

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP022657
EMBL· GenBank· DDBJ
ASS75915.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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