A0A223CZF4 · A0A223CZF4_9BACL

Function

function

Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Features

Showing features for binding site.

160950100150200250300350400450500550600
TypeIDPosition(s)Description
Binding site182L-aspartate (UniProtKB | ChEBI)
Binding site228L-aspartate (UniProtKB | ChEBI)
Binding site228-230ATP (UniProtKB | ChEBI)
Binding site237ATP (UniProtKB | ChEBI)
Binding site455L-aspartate (UniProtKB | ChEBI)
Binding site489ATP (UniProtKB | ChEBI)
Binding site496L-aspartate (UniProtKB | ChEBI)
Binding site541-544ATP (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytoplasm
Molecular Functionaspartate-tRNA ligase activity
Molecular FunctionATP binding
Molecular Functionnucleic acid binding
Molecular Functiontransferase activity
Biological Processaspartyl-tRNA aminoacylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Aspartate--tRNA ligase
  • EC number
  • Alternative names
    • Aspartyl-tRNA synthetase
      (AspRS
      )

Gene names

    • Name
      aspS
    • ORF names
      CIG75_06865

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • THMBR28
  • Taxonomic lineage
    Bacteria > Bacillota > Bacilli > Bacillales > Alicyclobacillaceae > Tumebacillus

Accessions

  • Primary accession
    A0A223CZF4

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain149-562Aminoacyl-transfer RNA synthetases class-II family profile
Region206-209Aspartate

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    609
  • Mass (Da)
    68,823
  • Last updated
    2017-10-25 v1
  • Checksum
    2856B5BA75D00BBA
MSEQQTLFRTHNAGELRKEHVGQSVVLNGWVQRRRDLGNLIFIDLRDRSGFAQAVFQPSEDEQHQLLMAQGDKLRSEFVIAVEGVVAAREAANTKIPTGEIEVKVTKIEILNAAKTTPFYIQDNIEVDENLRLKYRYLDLRRAEMQKIFLLRSKVTTYMRNFMDQNSFIEVETPILTKSTPEGARDYLVPSRVHPGEFYALPQSPQLFKQLLMVSGFERYYQIARCFRDEDLRADRQPEFTQIDIEQSFLSMEQFQAMMEELMTGVFKATIGVDIPRPFPRITYGEAMARYGSDKPDIRFGLELQDLTEQVRGSGFKVFNLAIENGGQVKCIVAPGCATYSRKQIDELEAFVKRYGAKGMAWIAVQEEGVKSPIAKFFSEEELAAIIERAGAQKGDLLLFAADSKKVVADSLGALRSKLGKELGLIDESEFKFIWVTEFPLLEHDEEANRYVAAHHPFTMPMEEDLHLLETDPANVRAKAYDLALNGFELGGGSMRIFNREIQERMFQALGFSLEEAWEQFGFLLEAFEYGTPPHGGIALGLDRMIMIMAGRQSLRDTIAFPKTTSASDLMTNAPSPVVIEQLDSLHIALGGKATTSIEKQEAEETEAK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
CP022657
EMBL· GenBank· DDBJ
ASS74721.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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