A0A218N6S8 · A0A218N6S8_ECOLX

  • Protein
    Diacylglycerol kinase
  • Gene
    dgkA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Mn2+, Zn2+, Cd2+ and Co2+ support activity to lesser extents.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site11substrate
Binding site18ATP (UniProtKB | ChEBI)
Binding site30ATP (UniProtKB | ChEBI)
Binding site30a divalent metal cation (UniProtKB | ChEBI)
Binding site32-36substrate
Active site71Proton acceptor
Binding site71substrate
Binding site78ATP (UniProtKB | ChEBI)
Binding site78a divalent metal cation (UniProtKB | ChEBI)
Binding site87-89ATP (UniProtKB | ChEBI)
Binding site96-97ATP (UniProtKB | ChEBI)
Binding site100substrate

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular FunctionATP binding
Molecular FunctionATP-dependent diacylglycerol kinase activity
Molecular Functionmetal ion binding
Biological Processphosphatidic acid biosynthetic process
Biological Processphosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Diacylglycerol kinase
  • EC number

Gene names

    • Name
      dgkA
    • ORF names
      BvCmsNSP007_00572
      , BvCmsSIP010_03336
      , D9C02_24410
      , FTV93_28325

Encoded on

  • Plasmid pCHL5009T-102k-mcr3
  • Plasmid pNCYU-26-73-3_MCR3
  • Plasmid pWJ1
  • Plasmid pchl5009t-102k-mcr3
  • Plasmid pncyu-26-73-3_mcr3

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • WJ1
    • NS-P007
    • SI-P010
    • CHL5009T
    • NCYU-26-73
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Escherichia

Accessions

  • Primary accession
    A0A218N6S8
  • Secondary accessions
    • A0A238BGW6
    • A0A2A2XSM8

Proteomes

    • Identifier
    • Component
      Plasmid pCHL5009T-102k-mcr3
    • Identifier
    • Component
      Plasmid pncyu-26-73-3_mcr3

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane31-51Helical
Transmembrane98-117Helical

Keywords

Family & Domains

Sequence similarities

Belongs to the bacterial diacylglycerol kinase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    126
  • Mass (Da)
    13,837
  • Last updated
    2017-09-27 v1
  • MD5 Checksum
    568FD6B1A6C19D849378C19219E9E497
MAKPGATGITRIIHATNYSMKGLSSAWRHEAAFRQELLLIVLLMPLAFFVGDGLNQILLLMVISWLVVIVEILNSAIEAVVDRIGSEHHELSGRAKDMGSAAVFIALMLNAIVWGALTGRNLLTWW

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
KY924928
EMBL· GenBank· DDBJ
ASF81897.1
EMBL· GenBank· DDBJ
Genomic DNA
CP032937
EMBL· GenBank· DDBJ
AYM25022.1
EMBL· GenBank· DDBJ
Genomic DNA
BGDN01000026
EMBL· GenBank· DDBJ
GDP60496.1
EMBL· GenBank· DDBJ
Genomic DNA
BGIE01000041
EMBL· GenBank· DDBJ
GDV31484.1
EMBL· GenBank· DDBJ
Genomic DNA
CP042618
EMBL· GenBank· DDBJ
QED76429.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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