A0A212D3R3 · A0A212D3R3_CEREH

Function

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

  • ADP + H2O = AMP + phosphate + H+
    This reaction proceeds in the forward direction.
  • AMP + H2O = adenosine + phosphate
    This reaction proceeds in the forward direction.
  • ATP + H2O = ADP + phosphate + H+
    This reaction proceeds in the forward direction.
  • N-phosphocreatine + H2O = creatine + phosphate
    This reaction proceeds in the forward direction.
    EC:3.9.1.1 (UniProtKB | ENZYME | Rhea)
  • phosphoethanolamine + H2O = ethanolamine + phosphate
    This reaction proceeds in the forward direction.
  • pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate
    This reaction proceeds in the forward direction.
  • a phosphate monoester + H2O = an alcohol + phosphate
    This reaction proceeds in the forward direction.
    EC:3.1.3.1 (UniProtKB | ENZYME | Rhea)
  • diphosphate + H2O = 2 phosphate + H+
    This reaction proceeds in the forward direction.

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Note: Binds 1 Mg2+ ion.
Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 2 Zn2+ ions.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site60Mg2+ (UniProtKB | ChEBI)
Binding site60Zn2+ 2 (UniProtKB | ChEBI)
Active site110Phosphoserine intermediate
Binding site171Mg2+ (UniProtKB | ChEBI)
Binding site173Mg2+ (UniProtKB | ChEBI)
Binding site332Mg2+ (UniProtKB | ChEBI)
Binding site337Zn2+ 2 (UniProtKB | ChEBI)
Binding site341Zn2+ 2 (UniProtKB | ChEBI)
Binding site378Zn2+ 2 (UniProtKB | ChEBI)
Binding site379Zn2+ 2 (UniProtKB | ChEBI)
Binding site454Zn2+ 2 (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentmitochondrial intermembrane space
Cellular Componentmitochondrial membrane
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular FunctionADP phosphatase activity
Molecular Functionalkaline phosphatase activity
Molecular FunctionATP hydrolysis activity
Molecular Functioninorganic diphosphate phosphatase activity
Molecular Functionmetal ion binding
Molecular Functionphosphoamidase activity
Molecular Functionphosphoethanolamine phosphatase activity
Molecular Functionpyridoxal phosphatase activity
Biological Processdephosphorylation

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Alkaline phosphatase
  • EC number

Gene names

    • ORF names
      Celaphus_00014740

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Laurasiatheria > Artiodactyla > Ruminantia > Pecora > Cervidae > Cervinae > Cervus

Accessions

  • Primary accession
    A0A212D3R3

Proteomes

Subcellular Location

Cell membrane
; Lipid-anchor, GPI-anchor
Extracellular vesicle membrane
; Lipid-anchor, GPI-anchor
Mitochondrion membrane
; Lipid-anchor, GPI-anchor

Keywords

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-17
ChainPRO_501232947418-524Alkaline phosphatase

Keywords

Interaction

Subunit

Homodimer.

Family & Domains

Sequence similarities

Belongs to the alkaline phosphatase family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    524
  • Mass (Da)
    57,301
  • Last updated
    2017-09-27 v1
  • Checksum
    2A86C8CC5976840D
MISPFLVLAIGTCLTNCLVPEKEKDPKYWREQAQQTLKNALRLQTLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLHHNPGEETRLEMDKFPYVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTVGVSAATQRSQCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSASYAHSADRDWYSDNEMPPEALSQGCKDIAYQLMHNVKDIEVIMGGGRKYMFPKNRTDVEYELDEKARGTRLDGLNLIDIWKSFKPKHKHSHYVWNRTDLLALDPHTVDYLLGLFEPGDMQYELNRNNVTDPSLSEMVEMAIKILNKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDQAIGQAGAMTSVEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMVSDTDKKPFTAILYGNGPGYKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFAKGPMAHLLHGVHEQNYIPHVMAYAACIGANRDHCASASSSSSPAPGPLLLLLALLPLGSLF

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MKHE01000008
EMBL· GenBank· DDBJ
OWK12897.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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