A0A210QLW4 · A0A210QLW4_MIZYE

Function

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

heme b (UniProtKB | Rhea| CHEBI:60344 )

Pathway

Lipid metabolism; prostaglandin biosynthesis.

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site112substrate
Active site199Proton acceptor
Active site376For cyclooxygenase activity
Binding site379Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentneuron projection
Molecular Functionheme binding
Molecular Functionmetal ion binding
Molecular Functionoxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Molecular Functionperoxidase activity
Molecular Functionprostaglandin-endoperoxide synthase activity
Biological Processcyclooxygenase pathway
Biological Processresponse to oxidative stress

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    prostaglandin-endoperoxide synthase
  • EC number

Gene names

    • ORF names
      KP79_PYT04524

Organism names

Accessions

  • Primary accession
    A0A210QLW4

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

Type
IDPosition(s)Description
Signal1-23
ChainPRO_501237451424-586prostaglandin-endoperoxide synthase
Disulfide bond28↔38

Keywords

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain24-61EGF-like

Sequence similarities

Belongs to the prostaglandin G/H synthase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    586
  • Mass (Da)
    67,388
  • Last updated
    2017-09-27 v1
  • Checksum
    3A1FAF49919A391B
MQDLQQGCRLLVVLVVVTGMVSANTSCCSYPCENGGVCMTTGMEGFQCDCTSTDFYGTLCETPTFLKRVKLWLKPSPDTTHYLLTHYNWLWDTVNSVNFLRNAVMKKVYTLRSDMIDSPVTYTSEHSYITLDANFNTTYYARTLPPVPYNCPTPMGVWGKKEMPDVDRIVKKFFVRKKFLPEPMGTSALFSFFAQHFTHQFFKTDVKNGPQYQWGGHGVDVTHVYGKDKDAEAKLRTFKDGKLKTQLIQGEEYPPLEKDAPVDMVYPPGTPEERRFAIGQKVFGLLPGLFMYATIWLREHNRVCDILKTEHPDWDDERLYQTGKLVILGETIKIVIEDYVQHLSHYNYQLLFRPELLFGEQFQYQNRITVEFNHLYHWHPLMPSEFNVSGTTYSLREFVYHPEVVLKHGMHDFVDSLSRQRAGAFGPFNHGPLTIPVVTDLLKQGRQLRLQPYNQYRKKFNLPAFKTFEEMTGNKELAKALEEEYGDINAVEFYVGLIMEKRRYRSVFGSSIVEMGGPYSVKGLMANPICSPKYWKPSTFGGDVGFDIINTASLKKLFCNNIKGDCPLVSFEVPDYVEGDVLHDEL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEDP02002985
EMBL· GenBank· DDBJ
OWF49726.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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