A0A210PVG6 · A0A210PVG6_MIZYE

Function

function

Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site362-367ATP (UniProtKB | ChEBI)
Binding site404-406ATP (UniProtKB | ChEBI)
Binding site450ATP (UniProtKB | ChEBI)
Binding site988ATP (UniProtKB | ChEBI)
Binding site1061-1063ATP (UniProtKB | ChEBI)
Binding site1068-1072ATP (UniProtKB | ChEBI)
Binding site1108ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionadenylate cyclase activity
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Biological Processadenylate cyclase-activating G protein-coupled receptor signaling pathway
Biological ProcesscAMP biosynthetic process
Biological Processintracellular signal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    adenylate cyclase
  • EC number

Gene names

    • ORF names
      KP79_PYT19026

Organism names

Accessions

  • Primary accession
    A0A210PVG6

Proteomes

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane130-150Helical
Transmembrane156-175Helical
Transmembrane187-204Helical
Transmembrane216-233Helical
Transmembrane640-662Helical
Transmembrane705-729Helical
Transmembrane780-798Helical
Transmembrane805-826Helical
Transmembrane846-867Helical

Keywords

  • Cellular component

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region33-63Disordered
Compositional bias42-56Polar residues
Domain357-484Guanylate cyclase
Region536-567Disordered
Domain936-1074Guanylate cyclase

Sequence similarities

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    1,133
  • Mass (Da)
    127,570
  • Last updated
    2017-09-27 v1
  • MD5 Checksum
    2FA5F4416A249E6D21828886132CD06E
MAKTPRSSKVLPQNMAVPISNIQENGNVFLVGNKNGDIKMTSPGSSRPGTANSGTRKSAWDRAREKYKEQQEQVKHLSKVTPIVGDDSVTSKQHLDLTTIASVFKSKRFKDIQLEWLFQRYFFKLNQTNLSILMALFCVTCVLSIISYYIGGATLPARGVNLGIALVTFVVLEIVCNRGTFFQQQMVVICYITLVLLCEFVVLMCLDTDPSSATDSAWSTVIFIYMLYTLLPIRMRLAVISGMGMSVLQIVCSIGKNYSDVFLWKQVVANSFLFICANIAGIFTHYPTEVAQRQAFLETRKCIEARLTTQRENQEQERLLLSVLPRHVAMEMKADIAGKPKDTMFHKIYIQRHENVSILFADMCGFTQLSSQCTAQELVQLLNELFARFDRLAADNHCLRIKILGDCYYCVSGLPDPRPDHAHCCVEMGLDMIQAISLVRDVTGADVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLANTMEAGGVPGLVHITEETLGFLNECYDVEPGNGGERNTYLRDNKITTYLIRGEQQRIKEKPKISPKKSARGRPPQGGGKSAAAKRMGFDDDPNANIHQKLGFGDHFESKNPEDEVNEYLGRAIDARSIDKLRSDHVTAFFLTFRKKDLEEKYSKVRDTMFTSHLGCTLLMLMCIAVIQLVILPHYKVYFKGNDFRYYLFHCFIETFQYTPKGLRSAATKIAVNKWLNQLVAMLAVSVLFVASIFAMFFLGTTSYIECLSSYYGISQSNFTISLVHLANITRVTETNICHQSDATTHFPEHFTFCVMLAMIGCAVYVQASSVFKLVVLLIMLFGYCIIVEVFFVNLYDNRDLLLVAESGKELRDPVSFIPLKWETVAVLVVLVGILFVQTQQVESTSRLDFLWKVQATDEKEEMESLRAYNKRLVTNILPINVAEHFMKNTYKKDEDLYYLDSENSGVMFASITNFSEFYMELEGNNEGVECLRLLNEIIADFDEVLGDEKFGCIEKIKTIGSTYMAASGLTPQTNFSDMSHVVALAEYAFAIQAQLQYVNEHSFNNFKIRIGMNVGPVVSGVIGARKPHYDIWGNSVNVASRMDSTGLPNSIQVTQDMHNILSVRGYELKCRGIVKVKGKGDMTTYFLTGRPDGKIQSPLMPS

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias42-56Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEDP02005461
EMBL· GenBank· DDBJ
OWF40483.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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