A0A210PVG6 · A0A210PVG6_MIZYE
- Proteinadenylate cyclase
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1133 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
Catalytic activity
- ATP = 3',5'-cyclic AMP + diphosphate
Cofactor
Protein has several cofactor binding sites:
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 362-367 | ATP (UniProtKB | ChEBI) | |||
Binding site | 404-406 | ATP (UniProtKB | ChEBI) | |||
Binding site | 450 | ATP (UniProtKB | ChEBI) | |||
Binding site | 988 | ATP (UniProtKB | ChEBI) | |||
Binding site | 1061-1063 | ATP (UniProtKB | ChEBI) | |||
Binding site | 1068-1072 | ATP (UniProtKB | ChEBI) | |||
Binding site | 1108 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenylate cyclase activity | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | |
Biological Process | cAMP biosynthetic process | |
Biological Process | intracellular signal transduction |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameadenylate cyclase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Pteriomorphia > Pectinida > Pectinoidea > Pectinidae > Mizuhopecten
Accessions
- Primary accessionA0A210PVG6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 130-150 | Helical | |||
Transmembrane | 156-175 | Helical | |||
Transmembrane | 187-204 | Helical | |||
Transmembrane | 216-233 | Helical | |||
Transmembrane | 640-662 | Helical | |||
Transmembrane | 705-729 | Helical | |||
Transmembrane | 780-798 | Helical | |||
Transmembrane | 805-826 | Helical | |||
Transmembrane | 846-867 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 33-63 | Disordered | |||
Compositional bias | 42-56 | Polar residues | |||
Domain | 357-484 | Guanylate cyclase | |||
Region | 536-567 | Disordered | |||
Domain | 936-1074 | Guanylate cyclase | |||
Sequence similarities
Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,133
- Mass (Da)127,570
- Last updated2017-09-27 v1
- MD5 Checksum2FA5F4416A249E6D21828886132CD06E
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 42-56 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NEDP02005461 EMBL· GenBank· DDBJ | OWF40483.1 EMBL· GenBank· DDBJ | Genomic DNA |