A0A210PE85 · A0A210PE85_MIZYE

Function

function

ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Features

Showing features for binding site, active site.

1849100200300400500600700800
Type
IDPosition(s)Description
Binding site378-385ATP (UniProtKB | ChEBI)
Active site740
Active site783

GO annotations

AspectTerm
Cellular Componentperoxisomal matrix
Molecular FunctionATP binding
Molecular FunctionATP hydrolysis activity
Molecular FunctionATP-dependent peptidase activity
Molecular Functionserine-type endopeptidase activity
Biological Processprotein import into peroxisome matrix
Biological Processprotein processing
Biological Processprotein quality control for misfolded or incompletely synthesized proteins
Biological Processprotein targeting to peroxisome

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Lon protease homolog 2, peroxisomal
  • EC number

Gene names

    • ORF names
      KP79_PYT14193

Organism names

Accessions

  • Primary accession
    A0A210PE85

Proteomes

Subcellular Location

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias, motif.

Type
IDPosition(s)Description
Domain11-222Lon N-terminal
Region585-619Disordered
Compositional bias586-606Basic and acidic residues
Domain651-834Lon proteolytic
Motif847-849Microbody targeting signal

Sequence similarities

Belongs to the peptidase S16 family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    849
  • Mass (Da)
    93,508
  • Last updated
    2017-09-27 v1
  • Checksum
    F14868356E7B91A5
MASAITIPRRLPLLLVADNVLLPGSSMRIPVKSMRNMNMVKGRLLSRNTLSSTIIGVIPRDPSDEQGDDLSSIHHIGTAAVVVQVTGTNWPKPAYTLLVTGLCRFKLQELLQEAPYPVATVNQLDKLPGLIDDNINMKNMGELDVLAENFREQASKLVDMLDISIPVVAKLKKMLEKLPDQHLPDICAAIVKASYSEKIQVLDAIDLTERFKKALPLLMRQIEGLKLLQKTRKDKFEIITKKEGSNRPGNMKRMFGKISSDLEEDEDGDIDELMDLEQKIKAADMPEHALKAAMKEFKRMKKMPQQMPEHAMIRNYLDLMVELPWSKHSKDALDIAQARKDMDEDHYGMEKPKKRVLEYLAVRQLKQTLRGPILCFIGPPGVGKTSIGKSIAHTLGREFYRISLGGVCDQSDIRGHRRTYIGSMPGRILQGLKLVGTNNPVFLLDEVDKLGKSLHGDPAAALLEVLDPAQNDSFTDHYLNVPFDLSQVLFIATANNMATIPPALLDRMELIQIPGYTQEEKVNIADRHLIPKQLKEHGLTAEQIQIPTDTVQLIASKYTREAGVRNLERKIGGVCRAVAVRVAEASPKSKGDKPAPEVDKKQIDNESVSESMSQEASTLAHPPEMPFVIDEVALEDILGPPQFESEVSQRLSQPGVAVGMAWTPMGGEILFVEATRMDGEGKLILTGQLGDVMKESANLALNWVRSNAHKLGLSGILSNASKKDTHIHFPAGAVGKDGPSAGVTVVTVLVSLLSKQCVRSDTAMTGEITLRGLVLPVGGIKEKVLAAHRAGLRRIILPKRNEKDLLEIPNNVRNDLAIVLVTRLEDVLNAAFDDGFPSVVSEHSVPSKL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias586-606Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NEDP02076750
EMBL· GenBank· DDBJ
OWF34794.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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