A0A210PE85 · A0A210PE85_MIZYE
- ProteinLon protease homolog 2, peroxisomal
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids849 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 378-385 | ATP (UniProtKB | ChEBI) | |||
Active site | 740 | ||||
Active site | 783 | ||||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | peroxisomal matrix | |
Molecular Function | ATP binding | |
Molecular Function | ATP hydrolysis activity | |
Molecular Function | ATP-dependent peptidase activity | |
Molecular Function | serine-type endopeptidase activity | |
Biological Process | protein import into peroxisome matrix | |
Biological Process | protein processing | |
Biological Process | protein quality control for misfolded or incompletely synthesized proteins | |
Biological Process | protein targeting to peroxisome |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameLon protease homolog 2, peroxisomal
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Metazoa > Spiralia > Lophotrochozoa > Mollusca > Bivalvia > Autobranchia > Pteriomorphia > Pectinida > Pectinoidea > Pectinidae > Mizuhopecten
Accessions
- Primary accessionA0A210PE85
Proteomes
Subcellular Location
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias, motif.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 11-222 | Lon N-terminal | |||
Region | 585-619 | Disordered | |||
Compositional bias | 586-606 | Basic and acidic residues | |||
Domain | 651-834 | Lon proteolytic | |||
Motif | 847-849 | Microbody targeting signal | |||
Sequence similarities
Belongs to the peptidase S16 family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length849
- Mass (Da)93,508
- Last updated2017-09-27 v1
- ChecksumF14868356E7B91A5
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 586-606 | Basic and acidic residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NEDP02076750 EMBL· GenBank· DDBJ | OWF34794.1 EMBL· GenBank· DDBJ | Genomic DNA |