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A0A1Z9PRG0 · A0A1Z9PRG0_9FLAO

Function

function

Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

FAD (UniProtKB | Rhea| CHEBI:57692 )

Pathway

Cofactor biosynthesis; NAD+ biosynthesis; quinolinate from L-kynurenine: step 1/3.

GO annotations

AspectTerm
Molecular FunctionFAD binding
Molecular Functionkynurenine 3-monooxygenase activity
Biological Process'de novo' NAD biosynthetic process from tryptophan
Biological Processanthranilate metabolic process
Biological Processkynurenine metabolic process
Biological Processquinolinate biosynthetic process
Biological Processtryptophan catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Kynurenine 3-monooxygenase
  • EC number
  • Alternative names
    • Kynurenine 3-hydroxylase

Gene names

    • Name
      kmo
    • ORF names
      CBD88_05580

Organism names

Accessions

  • Primary accession
    A0A1Z9PRG0

Proteomes

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain4-323FAD-binding

Sequence similarities

Belongs to the aromatic-ring hydroxylase family. KMO subfamily.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    445
  • Mass (Da)
    50,869
  • Last updated
    2017-11-22 v1
  • MD5 Checksum
    78D4954A85544F0E811EAF669FFF9F9E
MEKKIIIVGAGLAGSLCALYMLQRGYNVTVYERRSDMRKSVMTAGRSINLALSKRGWTALKKVGIEDRVMEISIPMPKRIMHDLEGKLTDQYYGNEDQAIYSVPRGELNVLLMNLAEKNGAQIFFNHKCVDVNMERAELTLTNTLEDSNINIKCDLIVGADGAFSAVRDKMTRQDRFQFSQYYIDHGYKELLIPANDDGSHKIEKHALHIWPRGNFMLIALPNLDGSYTCTLFSPFEGEDSFKELNTPKKVTTFFNKVFKDFTPLIPDLVDQFFNNPTASLGIFKCYPWHIKGHCVLIGDSAHATVPFYGQGMNASFEDCRVLDELIENYSEDFSLVLREFSKSRKPNGDGLQDLSLHNFIVMRDKTADPKFLLQKKIEQKFSQLYPHKWVPLYTMVSFTNISYSDAWKIGMSQEKLMADIMSIENIDELWDSDAVMQKMLDLSI

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
NHJZ01000081
EMBL· GenBank· DDBJ
OUW94504.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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