A0A1Z9PRG0 · A0A1Z9PRG0_9FLAO
- ProteinKynurenine 3-monooxygenase
- Genekmo
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids445 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
Catalytic activity
- L-kynurenine + NADPH + O2 + H+ = 3-hydroxy-L-kynurenine + NADP+ + H2O
Cofactor
Pathway
Cofactor biosynthesis; NAD+ biosynthesis; quinolinate from L-kynurenine: step 1/3.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | FAD binding | |
Molecular Function | kynurenine 3-monooxygenase activity | |
Biological Process | 'de novo' NAD biosynthetic process from tryptophan | |
Biological Process | anthranilate metabolic process | |
Biological Process | kynurenine metabolic process | |
Biological Process | quinolinate biosynthetic process | |
Biological Process | tryptophan catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameKynurenine 3-monooxygenase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Bacteroidota > Flavobacteriia > Flavobacteriales
Accessions
- Primary accessionA0A1Z9PRG0
Proteomes
Structure
Sequence
- Sequence statusComplete
- Length445
- Mass (Da)50,869
- Last updated2017-11-22 v1
- MD5 Checksum78D4954A85544F0E811EAF669FFF9F9E
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
NHJZ01000081 EMBL· GenBank· DDBJ | OUW94504.1 EMBL· GenBank· DDBJ | Genomic DNA |