Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategorySequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (AUG-2024)Cited in99+
Genetic determinants of micronucleus formation in vivo.Adams D.J., Barlas B., McIntyre R.E., Salguero I., van der Weyden L., Barros A., Vicente J.R., Karimpour N., Haider A.[...], White J.K.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCNature 627:130-136 (2024)Mapped to99+
Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice.Wei Y., Wang X., Ma Z., Xiang P., Liu G., Yin B., Hou L., Shu P., Liu W., Peng X.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCiScience 27:108706-108706 (2024)Mapped to61
SIRT5-related lysine demalonylation of GSTP1 contributes to cardiomyocyte pyroptosis suppression in diabetic cardiomyopathy.Wei C., Shi M., Dong S., Li Z., Zhao B., Liu D., Li G., Cen J., Yu L.[...], Shi L.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCInt J Biol Sci 20:585-605 (2024)Mapped to10
Histone malonylation is regulated by SIRT5 and KAT2A.Zhang R., Bons J., Scheidemantle G., Liu X., Bielska O., Carrico C., Rose J., Heckenbach I., Scheibye-Knudsen M.[...], Verdin E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCiScience 26:106193-106193 (2023)Mapped to7
SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis.Mao J., Wang D., Wang D., Wu Q., Shang Q., Gao C., Wang H., Wang H., Du M.[...], Luo Z.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCExp Mol Med 55:253-268 (2023)Mapped to9
Sirtuin 5 levels are limiting in preserving cardiac function and suppressing fibrosis in response to pressure overload.Guo A.H., Baliira R., Skinner M.E., Kumar S., Andren A., Zhang L., Goldsmith R.S., Michan S., Davis N.J.[...], Lombard D.B.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCSci Rep 12:12258-12258 (2022)Mapped to7
Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin.Head P.E., Myung S., Chen Y., Schneller J.L., Wang C., Duncan N., Hoffman P., Chang D., Gebremariam A.[...], Venditti C.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCSci Transl Med 14:eabn4772-eabn4772 (2022)Mapped to15
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice.Bhatt D.P., Mills C.A., Anderson K.A., Henriques B.J., Lucas T.G., Francisco S., Liu J., Ilkayeva O.R., Adams A.E.[...], Hirschey M.D.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCJ Biol Chem 298:101723-101723 (2022)Mapped to13
Sirtuin 5 is Dispensable for CD8<sup>+</sup> T Cell Effector and Memory Differentiation.Duan Q., Ding J., Li F., Liu X., Zhao Y., Yu H., Liu Y., Zhang L.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCFront Cell Dev Biol 9:761193-761193 (2021)Mapped to7
The enzyme activity of mitochondrial trifunctional protein is not altered by lysine acetylation or lysine succinylation.Zhang Y., Goetzman E.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCPLoS One 16:e0256619-e0256619 (2021)Mapped to17
Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression.Hu T., Shukla S.K., Vernucci E., He C., Wang D., King R.J., Jha K., Siddhanta K., Mullen N.J.[...], Singh P.K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCGastroenterology 161:1584-1600 (2021)Mapped to31
Pharmacological and genetic perturbation establish SIRT5 as a promising target in breast cancer.Abril Y.L.N., Fernandez I.R., Hong J.Y., Chiang Y.L., Kutateladze D.A., Zhao Q., Yang M., Hu J., Sadhukhan S.[...], Weiss R.S.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCOncogene 40:1644-1658 (2021)Mapped to14
Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.Goetzman E.S., Bharathi S.S., Zhang Y., Zhao X.J., Dobrowolski S.F., Peasley K., Sims-Lucas S., Monga S.P.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCSci Rep 10:18367-18367 (2020)Mapped to9
Impact of the Dual Deletion of the Mitochondrial Sirtuins SIRT3 and SIRT5 on Anti-microbial Host Defenses.Heinonen T., Ciarlo E., Le Roy D., Roger T.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCFront Immunol 10:2341-2341 (2019)Mapped to14
Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI.Chiba T., Peasley K.D., Cargill K.R., Maringer K.V., Bharathi S.S., Mukherjee E., Zhang Y., Holtz A., Basisty N.[...], Sims-Lucas S.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCJ Am Soc Nephrol 30:2384-2398 (2019)Mapped to7
SIRT5 Regulates Brown Adipocyte Differentiation and Browning of Subcutaneous White Adipose Tissue.Shuai L., Zhang L.N., Li B.H., Tang C.L., Wu L.Y., Li J., Li J.Y.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCDiabetes 68:1449-1461 (2019)Mapped to7
Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.Wang G., Meyer J.G., Cai W., Softic S., Li M.E., Verdin E., Newgard C., Schilling B., Kahn C.R.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCMol Cell 74:844-857.e7 (2019)Mapped to8
The absence of SIRT3 and SIRT5 promotes the acetylation of lens proteins and improves the chaperone activity of alpha-crystallin in mouse lenses.Nandi S.K., Nahomi R.B., Harris P.S., Michel C.R., Fritz K.S., Nagaraj R.H.View abstractCategoriesFunction, PTM / ProcessingSourceMGI: 1915596PubMedEurope PMCExp Eye Res 182:1-9 (2019)Mapped to19
Combined SIRT3 and SIRT5 deletion is associated with inner retinal dysfunction in a mouse model of type 1 diabetes.Lin J.B., Lin J.B., Chen H.C., Chen T., Apte R.S.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1915596PubMedEurope PMCSci Rep 9:3799-3799 (2019)Mapped to17
Respiratory Phenomics across Multiple Models of Protein Hyperacylation in Cardiac Mitochondria Reveals a Marginal Impact on Bioenergetics.Fisher-Wellman K.H., Draper J.A., Davidson M.T., Williams A.S., Narowski T.M., Slentz D.H., Ilkayeva O.R., Stevens R.D., Wagner G.R.[...], Muoio D.M.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCCell Rep 26:1557-1572.e8 (2019)Mapped to17
Sirtuin 5 Deficiency Does Not Compromise Innate Immune Responses to Bacterial Infections.Heinonen T., Ciarlo E., Theroude C., Pelekanou A., Herderschee J., Le Roy D., Roger T.View abstractCategoryFunctionSourceMGI: 1915596PubMedEurope PMCFront Immunol 9:2675-2675 (2018)Mapped to7