Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L.[...], Ponting C.P.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol. 7:E1000112-E1000112 (2009)Cited in99+99+
A tissue-specific atlas of mouse protein phosphorylation and expression.Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R., Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.View abstractCited forIDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]CategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCCell 143:1174-1189 (2010)Cited in99+99+Mapped to6
Modernizing reference genome assemblies.Church D.M., Schneider V.A., Graves T., Auger K., Cunningham F., Bouk N., Chen H.C., Agarwala R., McLaren W.M.[...], Hubbard T.Cited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]StrainC57BL/6JCategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCPLoS Biol 9:e1001091-e1001091 (2011)Cited in99+
No title available.EnsemblCited forIDENTIFICATIONStrainC57BL/6JSourceUniProtKB unreviewed (TrEMBL)Submission Submitted to UniProtKB (JUN-2024)Cited in99+
The fatty liver dystrophy mutant mouse: microvesicular steatosis associated with altered expression levels of peroxisome proliferator- regulated proteins.Rehnmark S., Giometti C.S., Slavin B.G., Doolittle M.H., Reue K.View abstractCategoriesPhenotypes & VariantsSourceMGI: 1891340PubMedEurope PMCJ Lipid Res 39:2209-2217 (1998)Mapped to10
Naturally occurring mutations in mice affecting lipid transport and metabolism.Reue K., Doolittle M.H.View abstractCategoriesPhenotypes & VariantsSourceMGI: 1891340PubMedEurope PMCJ Lipid Res 37:1387-1405 (1996)Mapped to16
Acads gene deletion in BALB/cByJ mouse strain occurred after 1981 and is not present in BALB/cByJ-fld mutant mice.Reue K., Cohen R.D.CategoriesFunction, SequencesSourceMGI: 1891340PubMedEurope PMCMamm Genome 7:694-695 (1996)Mapped to11
The fld mutation maps near to but distinct from the Apob locus on mouse chromosome 12.Rowe L.B., Sweet H.O., Gordon J.I., Birkenmeier E.H.CategoriesSequencesSourceMGI: 1891340PubMedEurope PMCMamm Genome 7:555-557 (1996)Mapped to14
Exploring lipin1 as a promising therapeutic target for the treatment of Duchenne muscular dystrophy.Jama A., Alshudukhi A.A., Burke S., Dong L., Kamau J.K., Morris B., Alkhomsi I.A., Finck B.N., Voss A.A., Ren H.View abstractAnnotationExploring lipin1 as a promising therapeutic target for the treatment of Duchenne muscular dystrophy.SourceGeneRif: 14245PubMedEurope PMCJ Transl Med 22:664-664 (2024)Mapped to8
Intermittent glucocorticoid treatment improves muscle metabolism via the PGC1alpha/Lipin1 axis in an aging-related sarcopenia model.Prabakaran A.D., McFarland K., Miz K., Durumutla H.B., Piczer K., El Abdellaoui Soussi F., Latimer H., Werbrich C., Chung H.J.[...], Quattrocelli M.View abstractSourceMGI: 1891340PubMedEurope PMCJ Clin Invest 134:e177427-e177427 (2024)Mapped to16
Haploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.Wang F., Liu Y., Dong Y., Zhao M., Huang H., Jin J., Fan L., Xiang R.View abstractAnnotationHaploinsufficiency of Lipin3 leads to hypertriglyceridemia and obesity by disrupting the expression and nucleocytoplasmic localization of Lipin1.SourceGeneRif: 14245PubMedEurope PMCFront Med 18:180-191 (2024)Mapped to13
Lipin-1 deficiency deteriorates defect of fatty acid beta-oxidation and lipid-related kidney damage in diabetic kidney disease.Lin S., Wang L., Jia Y., Sun Y., Qiao P., Quan Y., Liu J., Hu H., Yang B., Zhou H.View abstractAnnotationLipin-1 deficiency deteriorates defect of fatty acid beta-oxidation and lipid-related kidney damage in diabetic kidney disease.SourceGeneRif: 14245PubMedEurope PMCTransl Res 266:1-15 (2024)Mapped to8
Lipin1 plays complementary roles in myofibre stability and regeneration in dystrophic muscles.Jama A., Alshudukhi A.A., Burke S., Dong L., Kamau J.K., Voss A.A., Ren H.View abstractAnnotationLipin1 plays complementary roles in myofibre stability and regeneration in dystrophic muscles.CategoriesFunctionSourceGeneRif: 14245, MGI: 1891340PubMedEurope PMCJ Physiol 601:961-978 (2023)Mapped to13
Simultaneous monitoring of mouse grip strength, force profile, and cumulative force profile distinguishes muscle physiology following surgical, pharmacologic and diet interventions.Munier J.J., Pank J.T., Severino A., Wang H., Zhang P., Vergnes L., Reue K.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1891340PubMedEurope PMCSci Rep 12:16428-16428 (2022)Mapped to10
LPIN1 is a new target gene for essential hypertension.Fujiwara A., Ozawa M., Sumida K., Hirawa N., Yatsu K., Ichihara N., Haze T., Komiya S., Ohki Y.[...], Tamura K.View abstractAnnotationLPIN1 is a new target gene for essential hypertension.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14245PubMedEurope PMCJ Hypertens 40:536-543 (2022)Mapped to8
The middle lipin domain adopts a membrane-binding dimeric protein fold.Gu W., Gao S., Wang H., Fleming K.D., Hoffmann R.M., Yang J.W., Patel N.M., Choi Y.M., Burke J.E.[...], Airola M.V.View abstractAnnotationThe middle lipin domain adopts a membrane-binding dimeric protein fold.CategoriesFamily & Domains, InteractionSourceGeneRif: 14245PubMedEurope PMCNat Commun 12:4718-4718 (2021)Mapped to9
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.Bedogni F., Hevner R.F.View abstractCategoriesFunctionSourceMGI: 1891340PubMedEurope PMCFront Mol Neurosci 14:686034-686034 (2021)Mapped to99+
Myeloid-associated lipin-1 transcriptional co-regulatory activity is atheroprotective.Blackburn C.M.R., Schilke R.M., Vozenilek A.E., Chandran S., Bamgbose T.T., Finck B.N., Woolard M.D.View abstractAnnotationMyeloid-associated lipin-1 transcriptional co-regulatory activity is atheroprotective.CategoriesFunctionSourceGeneRif: 14245PubMedEurope PMCAtherosclerosis 330:76-84 (2021)Mapped to8
Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.Chambers K.T., Cooper M.A., Swearingen A.R., Brookheart R.T., Schweitzer G.G., Weinheimer C.J., Kovacs A., Koves T.R., Muoio D.M.[...], Finck B.N.View abstractAnnotationMyocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14245, MGI: 1891340PubMedEurope PMCJCI Insight 6:134340-134340 (2021)Mapped to18
MiR-99b-5p Attenuates Adipogenesis by Targeting SCD1 and Lpin1 in 3T3-L1 Cells.Xu Y., Chen X., Zhao C., Wang X., Cheng Y., Xi F., Yao X., Zhang L., Yang G., Yu T.View abstractAnnotationMiR-99b-5p Attenuates Adipogenesis by Targeting SCD1 and Lpin1 in 3T3-L1 Cells.CategoriesFunctionSourceGeneRif: 14245PubMedEurope PMCJ Agric Food Chem 69:2564-2575 (2021)Mapped to11
Proto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.Song L., Liu Z., Hu H.H., Yang Y., Li T.Y., Lin Z.Z., Ye J., Chen J., Huang X.[...], Lin S.C.View abstractAnnotationProto-oncogene Src links lipogenesis via lipin-1 to breast cancer malignancy.CategoriesFunction, InteractionSourceGeneRif: 14245, MGI: 1891340PubMedEurope PMCNat Commun 11:5842-5842 (2020)Mapped to15
Loss of membrane integrity drives myofiber death in lipin1-deficient skeletal muscle.Ramani Sattiraju S., Jama A., Alshudukhi A.A., Edward Townsend N., Reynold Miranda D., Reese R.R., Voss A.A., Ren H.View abstractAnnotationLoss of membrane integrity drives myofiber death in lipin1-deficient skeletal muscle.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14245PubMedEurope PMCPhysiol Rep 8:e14620-e14620 (2020)Mapped to8
Macrophage-Associated Lipin-1 Promotes beta-Oxidation in Response to Proresolving Stimuli.Schilke R.M., Blackburn C.M.R., Rao S., Krzywanski D.M., Finck B.N., Woolard M.D.View abstractAnnotationMacrophage-Associated Lipin-1 Promotes beta-Oxidation in Response to Proresolving Stimuli.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14245PubMedEurope PMCImmunohorizons 4:659-669 (2020)Mapped to12
Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization.Chandran S., Schilke R.M., Blackburn C.M.R., Yurochko A., Mirza R., Scott R.S., Finck B.N., Woolard M.D.View abstractAnnotationLipin-1 Contributes to IL-4 Mediated Macrophage Polarization.CategoriesFunction, Phenotypes & VariantsSourceGeneRif: 14245, MGI: 1891340PubMedEurope PMCFront Immunol 11:787-787 (2020)Mapped to12
Hypoxia‑inducible factor‑1alpha regulates Lipin1 differently in pre‑adipocytes and mature adipocytes.Kihira Y., Fujimura Y., Tomita S., Tamaki T., Sato E.View abstractAnnotationHypoxiainducible factor1alpha regulates Lipin1 differently in preadipocytes and mature adipocytes.CategoriesFunction, ExpressionSourceGeneRif: 14245PubMedEurope PMCMol Med Rep 22:559-565 (2020)Mapped to13