A0A1Y5KHZ0 · A0A1Y5KHZ0_9BACL
- ProteinHomoserine kinase
- GenethrB
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids336 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
Catalytic activity
- L-homoserine + ATP = O-phospho-L-homoserine + ADP + H+
Pathway
Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 98-108 | ATP (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | membrane | |
Molecular Function | ATP binding | |
Molecular Function | homoserine kinase activity | |
Biological Process | threonine biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameHomoserine kinase
- EC number
- Short namesHK ; HSK
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Bacillati > Bacillota > Bacilli > Bacillales > Paenibacillaceae > Paenibacillus
Accessions
- Primary accessionA0A1Y5KHZ0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 103-121 | Helical | |||
Transmembrane | 202-224 | Helical | |||
Keywords
- Cellular component
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 91-151 | GHMP kinase N-terminal | |||
Domain | 213-276 | GHMP kinase C-terminal | |||
Sequence similarities
Belongs to the GHMP kinase family. Homoserine kinase subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length336
- Mass (Da)35,430
- Last updated2017-08-30 v1
- MD5 ChecksumA490EDE66B819ED85A26CFB8ED516263
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MXQD01000004 EMBL· GenBank· DDBJ | OUS78276.1 EMBL· GenBank· DDBJ | Genomic DNA |