A0A1Y2T722 · A0A1Y2T722_SYMTR

Function

function

Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Pathway

Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.

Features

Showing features for binding site, site.

TypeIDPosition(s)Description
Binding site9substrate
Binding site9-10ATP (UniProtKB | ChEBI)
Binding site17ATP (UniProtKB | ChEBI)
Site17Transition state stabilizer
Binding site41substrate
Binding site73substrate
Binding site87substrate
Binding site88-90ATP (UniProtKB | ChEBI)
Binding site98ATP (UniProtKB | ChEBI)
Binding site123-129ATP (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionpantetheine-phosphate adenylyltransferase activity
Biological Processcoenzyme A biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Phosphopantetheine adenylyltransferase
  • EC number
  • Alternative names
    • Dephospho-CoA pyrophosphorylase
    • Pantetheine-phosphate adenylyltransferase
      (PPAT
      )

Gene names

    • Name
      coaD
    • ORF names
      A6D92_10890

Organism names

Accessions

  • Primary accession
    A0A1Y2T722

Proteomes

Subcellular Location

Keywords

Interaction

Subunit

Homohexamer.

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain5-133Cytidyltransferase-like

Sequence similarities

Belongs to the bacterial CoaD family.

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    162
  • Mass (Da)
    18,221
  • Last updated
    2017-08-30 v1
  • Checksum
    BD6004B5D5EA2C85
MIKAVCPGSFDPVTLGHLDIIERAARTFDEVVVAVLTNPRKEPLFTVEERVEMLKEATKHIPNVSVAAANGLLVDFARAQGCKVIVKGLRPIQDFEYEWQMGAVNRQLDPDIETCFFMSRIEYAHLSSSIVRELAYFGCPTDGLVPPSTAKRLREKFANRQR

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
LWLV01000901
EMBL· GenBank· DDBJ
OTA41013.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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