A0A1Y2T3N8 · A0A1Y2T3N8_SYMTR
- ProteinGTP cyclohydrolase 1
- GenefolE
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids176 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
Catalytic activity
- GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H+
Pathway
Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | GTP binding | |
Molecular Function | GTP cyclohydrolase I activity | |
Molecular Function | zinc ion binding | |
Biological Process | one-carbon metabolic process | |
Biological Process | tetrahydrobiopterin biosynthetic process | |
Biological Process | tetrahydrofolate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameGTP cyclohydrolase 1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageBacteria > Bacillota > Clostridia > Eubacteriales > Symbiobacteriaceae > Symbiobacterium
Accessions
- Primary accessionA0A1Y2T3N8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Interaction
Subunit
Homopolymer.
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 1-173 | GTP cyclohydrolase I | ||||
Sequence: MILEAVGEDPDREGLLETPRRVADFYEEVFAGLHRDPAERLTAIFNVDHEEMVIVRDISFQSMCEHHLLPFFGKAHVAYIPRKGRVVGLSKLARVVEDFSRRPQVQERLTAQIADLLMEKLNPLGVLVVVEAEHMCMTMRGVRKPGSFTITSAVRGVFQTSEATRAEAMALIR |
Sequence similarities
Belongs to the GTP cyclohydrolase I family.
Family and domain databases
Sequence
- Sequence statusComplete
- Length176
- Mass (Da)19,831
- Last updated2017-08-30 v1
- ChecksumEE1DA17F61CDBC84