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A0A1Y2SPT3 · A0A1Y2SPT3_9GAMM

  • Protein
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • Gene
    wecA
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    4/5

Function

function

Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Pathway

Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.
Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site153Mg2+ (UniProtKB | ChEBI)
Binding site217Mg2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular ComponentGram-negative-bacterium-type cell wall
Cellular Componentplasma membrane
Molecular Functionglycosyltransferase activity
Molecular Functionmagnesium ion binding
Molecular Functionmanganese ion binding
Molecular FunctionUDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity
Biological Processcell wall macromolecule biosynthetic process
Biological Processcell wall organization
Biological Processenterobacterial common antigen biosynthetic process
Biological ProcessO antigen biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
  • EC number
  • Alternative names
    • UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase
    • Undecaprenyl-phosphate GlcNAc-1-phosphate transferase

Gene names

    • Name
      wecA
    • ORF names
      Xbed_00922

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • DSM 4764
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus

Accessions

  • Primary accession
    A0A1Y2SPT3

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein
Cell membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane6-24Helical
Transmembrane45-65Helical
Transmembrane71-89Helical
Transmembrane101-119Helical
Transmembrane131-149Helical
Transmembrane161-178Helical
Transmembrane184-202Helical
Transmembrane214-233Helical
Transmembrane245-263Helical
Transmembrane294-312Helical
Transmembrane318-337Helical

Keywords

Interaction

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the glycosyltransferase 4 family. WecA subfamily.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    362
  • Mass (Da)
    40,443
  • Last updated
    2017-08-30 v1
  • MD5 Checksum
    A14910776D062BD1E5C765861F6B3D9B
MNIPSMSAEIFCVFIFSFAFLFVARKAAKKIGLVDKPNYRKRHHGLVPLVGGISVFFGICFAFVITKEFILHKWLYLSCAGILVFIGALDDRFDISVKIRATIQALVGISMMYFAGLKLESLGNTFGPWEMTLGPFSYVVTLFAVWAAINAFNMVDGIDGLLGGLSCVSFGALGILLYESGNTALAFWCFAFIAGILPYIFLNLGLVGKRFKVFMGDAGSTLIGFTIIWLLTATTQGESPAIRPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPDRQHIHHLIMRAGFTSRQAFILITLAAVLLASIGIIGERLSFVPEWVMLALFLLAFMLYGYCIKRAWRVARFIKRCKRRMRRATSHH

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
MUBK01000005
EMBL· GenBank· DDBJ
OTA20939.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

Disclaimer

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