A0A1Y2SPT3 · A0A1Y2SPT3_9GAMM
- ProteinUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
- GenewecA
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids362 (go to sequence)
- Protein existenceInferred from homology
- Annotation score4/5
Function
function
Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
Catalytic activity
- di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-di-trans,octa-cis-undecaprenyl diphosphate + UMP
Cofactor
Protein has several cofactor binding sites:
Pathway
Bacterial outer membrane biogenesis; LPS O-antigen biosynthesis.
Bacterial outer membrane biogenesis; enterobacterial common antigen biosynthesis.
Features
Showing features for binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 153 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 217 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | Gram-negative-bacterium-type cell wall | |
Cellular Component | plasma membrane | |
Molecular Function | glycosyltransferase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | manganese ion binding | |
Molecular Function | UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity | |
Biological Process | cell wall macromolecule biosynthetic process | |
Biological Process | cell wall organization | |
Biological Process | enterobacterial common antigen biosynthetic process | |
Biological Process | O antigen biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUndecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Morganellaceae > Xenorhabdus
Accessions
- Primary accessionA0A1Y2SPT3
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 6-24 | Helical | |||
Transmembrane | 45-65 | Helical | |||
Transmembrane | 71-89 | Helical | |||
Transmembrane | 101-119 | Helical | |||
Transmembrane | 131-149 | Helical | |||
Transmembrane | 161-178 | Helical | |||
Transmembrane | 184-202 | Helical | |||
Transmembrane | 214-233 | Helical | |||
Transmembrane | 245-263 | Helical | |||
Transmembrane | 294-312 | Helical | |||
Transmembrane | 318-337 | Helical | |||
Keywords
- Cellular component
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Sequence similarities
Belongs to the glycosyltransferase 4 family. WecA subfamily.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length362
- Mass (Da)40,443
- Last updated2017-08-30 v1
- MD5 ChecksumA14910776D062BD1E5C765861F6B3D9B
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
MUBK01000005 EMBL· GenBank· DDBJ | OTA20939.1 EMBL· GenBank· DDBJ | Genomic DNA |